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How to get fromSt. Louis to Southavenby bus (Greyhound, Flixbus), car, plane, or bus

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There are 4 ways to get from St. Louis to Southaven by bus (Greyhound, Flixbus), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus Greyhound US1173
    6h 23m
    $48–78
  2. Drive  295.1 mi

    1. Drive from St. Louis to Southavencar car 295.1 mi
    4h 47m
    $49–71
  3. Fly to Memphis

    1. Fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM)plane plane STL - MEM
    7h
    $134–804
  4. Fly to Jonesboro Municipal Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Jonesboro Municipal Airport (JBR)plane plane STL - JBR
    2. Take the bus from Jonesboro to Memphis Bus Stationbus bus
    6h 46m
    $154–466

St. Louis to Southaven by bus

Calendar12Weekly Buses
Duration6h 23mAverage Duration
Ticket$48Cheapest Price
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Comparing Your Travel Options

What companies run services between St. Louis, MO, USA and Southaven, MS, USA?

Greyhound USA operates a bus from St Louis Bus Station to Memphis Bus Station once daily. Tickets cost $50–80 and the journey takes 5h 30m. Flixbus USA also services this route 5 times a week. Alternatively, Delta, Southwest Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM) hourly.

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Bus operators

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Need to know: Greyhound

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