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How to get fromSt. Louis to Southavenby bus (Flixbus, Greyhound), car, plane, or bus

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There are 4 ways to get from St. Louis to Southaven by bus (Flixbus, Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus FlixBus 2510
    5h 39m
    $48–90

  2. Drive 295.1 mi

    1. Drive from St. Louis to Southavencar car 295.1 mi
    4h 47m
    $54–78

  3. Fly to Memphis

    1. Fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM)plane plane STL - MEM
    6h
    $134–754

  4. Fly to Jonesboro Municipal Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Jonesboro Municipal Airport (JBR)plane plane STL - JBR
    2. Take the bus from Jonesboro to Memphis Bus Stationbus bus
    6h 48m
    $164–528

St. Louis to Southaven by bus

Calendar14Weekly Buses
Duration5h 39mAverage Duration
Ticket$48Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Southaven.ExpandLaunch map view
  • Distance: 294.2 mi
  • Duration: 5h 39m

What companies run services between St. Louis, MO, USA and Southaven, MS, USA?

Flixbus USA operates a bus from St Louis Bus Station to Memphis Bus Station once daily. Tickets cost $45–80 and the journey takes 4h 45m. Greyhound USA also services this route once daily. Alternatively, Southwest Airlines, Delta, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM) hourly.

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