Rome2Rio

How to get fromSt. Louis to Southportby plane, car, bus, car ferry, train, or taxi

Find Transport to Southport

See all options

There are 7 ways to get from St. Louis to Southport by plane, car, bus, car ferry, train, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Myrtle Beach, drive

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR)plane plane STL - MYR
    2. Drive from Myrtle Beach (MYR) to Southportcar car
    4h 53m
    $94–450

  2. Bus, car ferry via Carbondale

    1. Take the bus from St. Louis to Carbondalebus bus
    2. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    4. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    5. Take the carferry from Fort Fisher, NC to Southport, NCcarferry car ferry
    26h 38m
    $153–311

  3. Train, bus, taxi via Petersburg

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Fayetteville Amtrak Stationtrain train
    4. Take the bus from Fayetteville Bus Station to Wilmington Cape Fear Public Transitbus bus
    5. Take the taxi from Wilmington Cape Fear Public Transit to Southporttaxi taxi
    35h 1m
    $519–1,043

  4. Drive 898.2 mi

    1. Drive from St. Louis to Southportcar car 898.2 mi
    16h 40m
    $164–237

  5. Fly to Wilmington International Airport, taxi

    1. Fly from Lambert–St. Louis International Airport (STL) to Wilmington International Airport (ILM)plane plane STL - ILM
    2. Take the taxi from Wilmington International Airport (ILM) to Southporttaxi taxi
    6h 18m
    $178–648

  6. Bus, car ferry

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    3. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    4. Take the carferry from Fort Fisher, NC to Southport, NCcarferry car ferry
    27h 13m
    $157–306

  7. Train, bus, taxi

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the bus from Raleigh Bus Station to Wilmington Cape Fear Public Transitbus bus
    4. Take the taxi from Wilmington Cape Fear Public Transit to Southporttaxi taxi
    35h 16m
    $521–1,025

Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR) flights

Calendar39Weekly Planes
Duration3h 50mAverage Duration
Ticket$82Cheapest Price
See schedules

Questions & Answers

Map of how to get from St. Louis to Southport.ExpandLaunch map view
  • Distance: 804.9 mi
  • Duration: 4h 53m

What companies run services between St. Louis, MO, USA and Southport, NC, USA?

There is no direct connection from St. Louis to Southport. However, you can take the train to LAMBERT AIRPORT TERMINAL #1 station, walk to Lambert–St. Louis International Airport (STL) airport, fly to Myrtle Beach (MYR), then drive to Southport. Alternatively, you can take a bus from St. Louis to Southport via Carbondale Intermodal Station, Atlanta Bus Station, Myrtle Beach Bus Station, Forden Station, Carolina Beach Rd NB at College Rd, Fort Fisher, NC, and Southport, NC in around 26h 38m.

Airlines
Train operators
Bus operators
Ferry operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound