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How to get fromSt. Louis to Twinsburgby plane, bus, train (Amtrak), bus (Flixbus), car, or bus (Greyhound)

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There are 7 ways to get from St. Louis to Twinsburg by plane, bus, train (Amtrak), bus (Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Cleveland-Hopkins International Airport, bus, line 32 bus

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Cleveland-Hopkins International Airport (CLE)plane plane STL - CLE
    2. Take the bus from Stokes-Windermere Station Bus Stop #3 to Southgate Transit Center Stop #4bus bus
    3. Take the bus from Southgate Transit Center to E. Aurora Rd @ Grande Villagebus bus
    6h 23m

  2. Fly to Akron

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Akron (CAK)plane plane STL - CAK
    9h 29m
    $84–454

  3. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to Cleveland Amtraktrain train Floridian / ...
    12h 36m
    $389–597

  4. Bus via Chicago (Flixbus)

    1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus N2521 / ...
    2. Take the bus from Chicago Bus Station to Robert K Pfaff Transit Center - Akronbus bus FlixBus N2641
    16h 40m
    $112–171

  5. Drive  546.9 mi

    1. Drive from St. Louis to Twinsburgcar car 546.9 mi
    9h 20m
    $94–135

  6. Fly to John Glenn Columbus International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to John Glenn Columbus International Airport (CMH)plane plane STL - CMH
    2. Take the bus from John Glenn Columbus Intnl Airport to Robert K Pfaff Transit Center - Akronbus bus
    9h 21m
    $106–570

  7. Bus

    1. Take the bus from St Louis Bus Station to Cambridge, OHbus bus Greyhound US0421
    2. Take the bus from Cambridge to Akronbus bus Bsb 13 / ...
    16h 55m
    $102–182

St. Louis to Twinsburg by bus (Flixbus)

Calendar10Weekly Buses
Duration16h 40mAverage Duration
Ticket$112Cheapest Price
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Comparing Your Travel Options

Map of how to get from St. Louis to Twinsburg.ExpandLaunch map view
  • Distance: 545.9 mi
  • Duration: 6h 23m

What companies run services between St. Louis, MO, USA and Twinsburg, OH, USA?

You can take a train from St. Louis to Twinsburg via Chicago Union Station and Cleveland Amtrak in around 12h 36m. Alternatively, you can take a bus from St Louis Bus Station to Darrow Rd @ Giant Eagle via Chicago Bus Station and RKP Transit Center in around 16h 40m.

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