There are 4 ways to get from St. Louis to Waltham by plane, train (Amtrak), bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Lambert–St. Louis International Airport (STL) to Boston Logan Airport (BOS)plane STL - BOS
5h 6m$362–852Bus
cheapest- Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus Greyhound US0421
- Take the bus from Manhattan, NY to Newton, MAbus Manhattan-Cambridge
29h 47m$184–325Train (Amtrak)
- Take the train from St. Louis to Chicago Union Stationtrain Lincoln Service / ...
- Take the train from Chicago Union Station to Bostontrain Lake Shore Limited
28h 17m$346–770Drive 1,142.4 mi
- Drive from St. Louis to Walthamcar 1,142.4 mi
20h 16m$209–302
St. Louis to Waltham by train and bus (Amtrak)
Questions & Answers
The cheapest way to get from St. Louis to Waltham is to bus which costs $180 - $330 and takes 29h 47m.
The fastest way to get from St. Louis to Waltham is to fly which takes 5h 6m and costs $360 - $850.
No, there is no direct bus from St. Louis station to Waltham. However, there are services departing from St Louis Bus Station and arriving at Newton, MA via Manhattan, NY. The journey, including transfers, takes approximately 29h 47m.
No, there is no direct train from St. Louis to Waltham. However, there are services departing from St. Louis and arriving at Boston via Chicago Union Station. The journey, including transfers, takes approximately 28h 17m.
The distance between St. Louis and Waltham is 1079 miles. The road distance is 1149.1 miles.
The best way to get from St. Louis to Waltham without a car is to train which takes 28h 17m and costs $340 - $800.
It takes approximately 5h 6m to get from St. Louis to Waltham, including transfers.
St. Louis to Waltham bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Waltham train services, operated by Amtrak, depart from St. Louis station.
The best way to get from St. Louis to Waltham is to fly which takes 5h 6m and costs $360 - $850. Alternatively, you can train, which costs $340 - $800 and takes 28h 17m, you could also bus, which costs $180 - $330 and takes 29h 47m.
What companies run services between St. Louis, MO, USA and Waltham, MA, USA?
American Airlines and Southwest Airlines fly from Lambert–St. Louis International Airport (STL) to Boston Logan Airport (BOS) every 4 hours. Alternatively, you can take a train from St. Louis to Washington St @ Bacon St via Chicago Union Station, Boston, and Saint James Ave @ Dartmouth St in around 28h 17m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Boston Logan Airport
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- $110–550
Flights from Lambert–St. Louis International Airport to Boston Logan Airport via Chicago Midway
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $120–600
Flights from Lambert–St. Louis International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 4h 35m
- When
- Sunday
- Estimated price
- $110–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $75–170
- Website
- Amtrak
Train from Chicago Union Station to Boston
- Ave. Duration
- 21h 54m
- Frequency
- Once daily
- Estimated price
- $270–600
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Port Authority Bus Terminal
- Ave. Duration
- 24h 45m
- Frequency
- 3 times a day
- Estimated price
- $140–280
- Website
- Greyhound
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More Questions & Answers
St. Louis to Waltham bus services, operated by Greyhound USA, arrive at Port Authority Bus Terminal station.
Waltham is 1h ahead of St. Louis. It is currently 11:09 AM in St. Louis and 12:09 PM in Waltham.
St. Louis to Waltham train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between St. Louis to Waltham is 1149 miles. It takes approximately 20h 16m to drive from St. Louis to Waltham.
There are 1655+ hotels available in Waltham.








