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How to get fromSt. Louis to West Chesterby plane, bus, train, train (Amtrak), or car

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There are 9 ways to get from St. Louis to West Chester by plane, bus, train, train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Philadelphia International Airport, line 104 bus

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Philadelphia International Airport (PHL)plane plane STL - PHL
    2. Take the bus from 69th St Transit Center to Chestnut St & Darlington Stbus bus
    5h 56m
    $172–1,112

  2. Fly to John F. Kennedy International Airport, train

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to John F. Kennedy International Airport (JFK)plane plane STL - JFK
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    7h 56m
    $132–1,068

  3. Bus, train

    1. Take the bus from St Louis Bus Station to Harrisburg Bus Stationbus bus Greyhound US0421
    2. Take the train from Harrisburg to Downingtown Amtraktrain train Keystone Service
    22h 48m
    $156–294

  4. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train
    3. Take the train from Pittsburgh Amtrak Station to Paoli Amtrak Stationtrain train
    24h 51m
    $345–728

  5. Drive 856.1 mi

    1. Drive from St. Louis to West Chestercar car 856.1 mi
    14h 37m
    $157–226

  6. Fly to Baltimore-Washington International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Baltimore-Washington International Airport (BWI)plane plane STL - BWI
    2. Take the train from BWI Thurgood Marshall to 30th Street Stationtrain train
    7h 23m
    $152–1,310

  7. Fly to Laguardia Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Laguardia Airport (LGA)plane plane STL - LGA
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    7h 49m
    $182–1,364

  8. Fly to Ronald Reagan Washington National Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Ronald Reagan Washington National Airport (DCA)plane plane STL - DCA
    2. Take the train from Washington Union Station to 30th Street Stationtrain train
    7h 28m
    $212–486

  9. Fly to Newark Liberty International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Newark Liberty International Airport (EWR)plane plane STL - EWR
    2. Take the train from Newark Liberty International Airport to 30th Street Stationtrain train
    7h 53m
    $404–864

St. Louis to West Chester by bus and train

Calendar21Weekly Services
Duration22h 48mAverage Duration
Ticket$156Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to West Chester.ExpandLaunch map view
  • Distance: 857.9 mi
  • Duration: 5h 56m

What companies run services between St. Louis, MO, USA and West Chester, PA, USA?

You can take a train from St. Louis to Chestnut St & Church St via Chicago Union Station, Pittsburgh Amtrak Station, Paoli Amtrak Station, and Lancaster Av & Valley Rd - FS in around 24h 51m.

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