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How to get fromSt. Louis to Wilkes-Barreby plane, bus (Greyhound), train, bus, or car

Find Transport to Wilkes-Barre

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There are 5 ways to get from St. Louis to Wilkes-Barre by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Wilkes-Barre/Scranton International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Wilkes-Barre/Scranton International Airport (AVP)plane plane STL - AVP
    6h 26m
    $182–718

  2. Bus

    cheapest
    1. Take the bus from St Louis Bus Station to Harrisburg Bus Stationbus bus Greyhound US0421
    2. Take the bus from Harrisburg, Pa to Wilkes Barre, Pabus bus 770
    23h 5m
    $144–296

  3. Train, bus

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Syracuse Regional Transportation Centertrain train
    3. Take the bus from Syracuse Bus Station to Scranton Bus Stationbus bus
    24h 3m
    $340–692

  4. Drive 865.5 mi

    1. Drive from St. Louis to Wilkes-Barrecar car 865.5 mi
    14h 34m
    $158–229

  5. Fly to Laguardia Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Laguardia Airport (LGA)plane plane STL - LGA
    2. Take the bus from Port Authority Bus Terminal to Wilkes-Barrebus bus
    8h 47m
    $210–540

St. Louis to Wilkes-Barre by bus

Calendar7Weekly Buses
Duration23h 5mAverage Duration
Ticket$144Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Wilkes-Barre.ExpandLaunch map view
  • Distance: 818.8 mi
  • Duration: 6h 26m

What companies run services between St. Louis, MO, USA and Wilkes-Barre, PA, USA?

United Airlines and American Airlines fly from Lambert–St. Louis International Airport (STL) to Wilkes-Barre/Scranton International Airport (AVP) every 4 hours. Alternatively, you can take a bus from St Louis Bus Station to Wilkes Barre, Pa via Harrisburg, Pa in around 23h 5m.

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