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How to get fromSt. Louis to Wilmingtonby plane, bus (Flixbus, Amtrak, Greyhound), car, taxi, bus, or bus (Greyhound, Flixbus)

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There are 7 ways to get from St. Louis to Wilmington by plane, bus (Flixbus, Amtrak, Greyhound), car, taxi, bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Wilmington International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Wilmington International Airport (ILM)plane plane STL - ILM
    5h 43m
    $116–570

  2. Fly to Myrtle Beach, bus

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR)plane plane STL - MYR
    2. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    6h 59m
    $110–480

  3. Bus via Carbondale

    1. Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus bus
    2. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Bus Station to Wilmington Cape Fear Public Transitbus bus
    23h 45m
    $156–312

  4. Drive 881.5 mi

    1. Drive from St. Louis to Wilmingtoncar car 881.5 mi
    16h 19m
    $161–233

  5. Fly to Albert J. Ellis Airport, taxi

    1. Fly from Lambert–St. Louis International Airport (STL) to Albert J. Ellis Airport (OAJ)plane plane STL - OAJ
    2. Take the taxi from Albert J. Ellis Airport (OAJ) to Wilmingtontaxi taxi
    6h 59m
    $232–712

  6. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Wilmington Cape Fear Public Transitbus bus
    24h 30m
    $156–307

  7. Bus #2

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    3. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    24h 44m
    $152–294

St. Louis to Wilmington by bus

Calendar10Weekly Buses
Duration23h 45mAverage Duration
Ticket$156Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Wilmington.ExpandLaunch map view
  • Distance: 775.5 mi
  • Duration: 5h 43m

What companies run services between St. Louis, MO, USA and Wilmington, NC, USA?

American Airlines, Delta, and United Airlines fly from Lambert–St. Louis International Airport (STL) to Wilmington International Airport (ILM) every 2 hours. Alternatively, you can take a bus from St Louis Bus Station to Market St WB at 4th St via Carbondale Intermodal Station, Atlanta Bus Station, Charlotte Bus Station, and Forden Station in around 23h 45m.

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