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How to get fromSt. Louis to Yazoo Cityby bus, train, car, or plane

Find Transport to Yazoo City

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There are 5 ways to get from St. Louis to Yazoo City by bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train via Carbondale

    best
    1. Take the bus from St. Louis to Carbondalebus bus Amtrak Thruway Connecting Service
    2. Take the train from Carbondale to Yazoo City Amtrak Stationtrain train City of New Orleans
    11h 37m
    $225–363

  2. Drive  461.8 mi

    cheapest
    1. Drive from St. Louis to Yazoo Citycar car 461.8 mi
    8h 11m
    $85–122

  3. Bus, train

    1. Take the bus from St Louis Bus Station to Jacksonbus bus Greyhound US1173
    2. Take the train from Jackson to Yazoo City Amtrak Stationtrain train City of New Orleans
    13h 41m
    $115–174

  4. Fly to Jackson/Vicksburg, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Jackson/Vicksburg (JAN)plane plane STL - JAN
    2. Take the train from Jackson to Yazoo City Amtrak Stationtrain train
    7h 3m
    $142–522

  5. Fly to Golden Triangle Regional Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Golden Triangle Regional Airport (GTR)plane plane STL - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Yazoo Citycar car
    8h 7m
    $112–502

St. Louis to Yazoo City by bus and train

Calendar7Weekly Services
Duration11h 37mAverage Duration
Ticket$225Cheapest Price
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Comparing Your Travel Options

Map of how to get from St. Louis to Yazoo City.ExpandLaunch map view
  • Distance: 489.7 mi
  • Duration: 11h 37m

What companies run services between St. Louis, MO, USA and Yazoo City, MS, USA?

There is no direct connection from St. Louis to Yazoo City. However, you can take the bus to Carbondale, walk to Carbondale, then take the train to Yazoo City Amtrak Station. Alternatively, you can take a bus from St Louis Bus Station to Yazoo City Amtrak Station via Jackson and Jackson in around 13h 41m.

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