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How to get fromSt. Louis to Zacatecasby plane, bus (Greyhound), train, bus, or car

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There are 7 ways to get from St. Louis to Zacatecas by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Zacatecas International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Zacatecas International Airport (ZCL)plane plane STL - ZCL
    8h 4m
    $4,543–18,693

  2. Fly to San Luis Potosí Airport, bus

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to San Luis Potosí Airport (SLP)plane plane STL - SLP
    2. Take the bus from San Luis Potosí to Zacatecasbus bus
    10h 56m
    $4,083–16,133

  3. Bus

    1. Take the bus from St Louis Bus Station to Oklahoma City Bus Stationbus bus Greyhound US1210
    2. Take the bus from Oklahoma to Zacatecasbus bus Omaha-Aguascalientes / ...
    34h 19m
    $5,536–7,393

  4. Train, bus

    1. Take the train from St. Louis to San Marcos Amtraktrain train Texas Eagle
    2. Take the bus from San Marcos to Zacatecasbus bus
    39h 11m
    $7,162–13,334

  5. Drive 2,373.9 km

    1. Drive from St. Louis to Zacatecascar car 2,373.9 km
    24h 39m
    $4,615–6,666

  6. Fly to Lic. Jesús Terán Peredo International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Lic. Jesús Terán Peredo International Airport (AGU)plane plane STL - AGU
    2. Take the bus from Aguascalientes to Zacatecasbus bus
    10h 37m
    $4,263–17,773

  7. Train, bus via Mesquite

    1. Take the train from St. Louis to Dallastrain train Texas Eagle
    2. Take the bus from Tornado Bus Co - Dallas I-30 to Zacatecasbus bus
    36h 30m
    $7,571–11,547

St. Louis to Zacatecas by train, tram, and bus

Calendar7Weekly Services
Duration36h 30mAverage Duration
Ticket$7,571Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Zacatecas.ExpandLaunch map view
  • Distance: 2,159.7 km
  • Duration: 8h 4m

What companies run services between St. Louis, MO, USA and Zacatecas, Mexico?

American Airlines, Southwest Airlines, and Volaris fly from Lambert–St. Louis International Airport (STL) to Zacatecas International Airport (ZCL) once daily. Alternatively, you can take a bus from St Louis Bus Station to Zacatecas via Oklahoma City Bus Station and Oklahoma in around 34h 19m.

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Want to know more about travelling around Mexico

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Need to know: Greyhound

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