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How to get fromSt. Marys to Florenceby taxi, train, bus (Flixbus), car, plane, or bus (Greyhound)

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There are 5 ways to get from St. Marys to Florence by taxi, train, bus (Flixbus), car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, train (Amtrak)

    best
    1. Take the taxi from St. Marys to Jacksonvilletaxi taxi
    2. Take the train from Jacksonville to Florence Stationtrain train Silver Meteor
    6h 56m
    $217–357

  2. Drive 281.7 mi

    cheapest
    1. Drive from St. Marys to Florencecar car 281.7 mi
    4h 40m
    $52–75

  3. Bus

    1. Take the bus from Yulee Park & Ride to JRTC - Express Selectbus bus Nassau
    2. Take the bus from Jacksonville to Florencebus bus FlixBus N2472
    7h 50m
    $127–183

  4. Taxi, fly

    1. Take the taxi from St. Marys to Jacksonville-Airport-JAXtaxi taxi
    2. Fly from Jacksonville (JAX) to Florence Regional Airport (FLO)plane plane JAX - FLO
    5h 34m
    $157–490

  5. Bus via Sumter (Greyhound)

    1. Take the bus from Kingsland to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Sumter Bus Stopbus bus
    3. Take the bus from Sumter Bus Stop to Florence Bus Stationbus bus
    9h 57m
    $83–144

Jacksonville (JAX) to Florence Regional Airport (FLO) flights

Calendar7Weekly Planes
Duration5h 43mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

Map of how to get from St. Marys to Florence.ExpandLaunch map view
  • Distance: 382 mi
  • Duration: 6h 56m

What companies run services between St. Marys, GA, USA and Florence, SC, USA?

You can take a vehicle from St. Marys to Florence via Yulee Park & Ride, JRTC - Express Select, Jacksonville, and Florence in around 7h 50m.

Airlines
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