There are 4 ways to get from St. Petersburg to Florence by train (Amtrak), bus (Flixbus, Greyhound), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Tampa to Kissimmee Amtrak Stationtrain Floridian
- Take the train from Kissimmee Amtrak Station to Florence Stationtrain Silver Meteor
13h 13m$245–463Fly
cheapest- Fly from Tampa (TPA) to Florence Regional Airport (FLO)plane TPA - FLO
8h 15m$85–408Bus
- Take the bus from 2Nd Ave Ne + Beach Drive to Marion Transit Parking Lotbus 100
- Take the bus from Tampa Bus Station to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Florencebus
13h 29m$99–164Drive 518.9 mi
- Drive from St. Petersburg to Florencecar 518.9 mi
8h 54m$95–137
Tampa (TPA) to Florence Regional Airport (FLO) flights
Questions & Answers
The cheapest way to get from St. Petersburg to Florence is to drive which costs $90 - $140 and takes 8h 54m.
The fastest way to get from St. Petersburg to Florence is to fly which takes 8h 15m and costs $85 - $410.
No, there is no direct bus from St. Petersburg to Florence. However, there are services departing from 2Nd Ave Ne + Beach Drive and arriving at Florence via Tampa Bus Station and Orlando Bus Station. The journey, including transfers, takes approximately 13h 29m.
No, there is no direct train from St. Petersburg to Florence station. However, there are services departing from Tampa and arriving at Florence Station via Kissimmee Amtrak Station. The journey, including transfers, takes approximately 13h 13m.
The distance between St. Petersburg and Florence is 607 miles. The road distance is 521.9 miles.
The best way to get from St. Petersburg to Florence without a car is to train which takes 13h 13m and costs $240 - $470.
It takes approximately 13h 13m to get from St. Petersburg to Florence, including transfers.
St. Petersburg to Florence bus services, operated by Pinellas Suncoast Transit Authority, depart from 2Nd Ave Ne + Beach Drive station.
St. Petersburg to Florence train services, operated by Amtrak, depart from Tampa station.
The best way to get from St. Petersburg to Florence is to train which takes 13h 13m and costs $240 - $470. Alternatively, you can bus, which costs $95 - $170 and takes 13h 29m, you could also fly, which costs $85 - $410 and takes 8h 15m.
What companies run services between St. Petersburg, FL, USA and Florence, SC, USA?
You can take a vehicle from St. Petersburg to Florence Station via Tampa and Kissimmee Amtrak Station in around 13h 13m. Alternatively, you can take a bus from 2Nd Ave Ne + Beach Drive to Florence via Marion Transit Parking Lot, Tampa Bus Station, Orlando Bus Station, and Florence in around 13h 29m.
- Website
- aa.com
Flights from Tampa to Florence Regional Airport via Charlotte
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $70–390
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Tampa to Kissimmee Amtrak Station
- Ave. Duration
- 1h 18m
- Frequency
- Once daily
- Estimated price
- $23–50
- Website
- Amtrak
Train from Kissimmee Amtrak Station to Florence Station
- Ave. Duration
- 10h 25m
- Frequency
- Once daily
- Estimated price
- $160–340
- Website
- Amtrak
- Phone
- +1 727-540-1900
- [email protected]
- Website
- Pinellas Suncoast Transit Authority
Bus from 2Nd Ave Ne + Beach Drive to Marion Transit Parking Lot
- Ave. Duration
- 1h 18m
- Frequency
- Hourly
- Estimated price
- $3
- Schedules at
- Pinellas Suncoast Transit Authority
- Adult
- $3
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Tampa Bus Station to Orlando Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Every 3 hours
- Estimated price
- $13–22
- Schedules at
- Flixbus USA
Bus from Orlando Bus Station to Florence
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- $70–120
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Tampa Bus Station to Orlando Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- Twice daily
- Estimated price
- $12–24
- Website
- Greyhound
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More Questions & Answers
St. Petersburg to Florence bus services, operated by Pinellas Suncoast Transit Authority, arrive at Marion Transit Parking Lot station.
St. Petersburg to Florence train services, operated by Amtrak, arrive at Kissimmee Amtrak Station.
Yes, the driving distance between St. Petersburg to Florence is 522 miles. It takes approximately 8h 54m to drive from St. Petersburg to Florence.
Book your St. Petersburg to Florence bus tickets online with Omio.
There are 47+ hotels available in Florence.