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How to get fromSt. Petersburg to Great Smoky Mountainsby bus, plane, car, or train

Find Transport to Great Smoky Mountains

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There are 7 ways to get from St. Petersburg to Great Smoky Mountains by bus, plane, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Sarasota–Bradenton International Airport, fly to Mcghee Tyson Airport, drive

    best
    1. Take the bus from Psta Grand Central Station to Desoto Station Parking For 12 & 203bus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Mcghee Tyson Airport (TYS)plane plane SRQ - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    6h 15m
    $190–1,127

  2. Fly Saint Petersburg–Clearwater International Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Asheville Regional Airport (AVL)plane plane PIE - AVL
    2. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    6h 4m
    $79–387

  3. Bus, drive

    1. Take the bus from 2Nd Ave Ne + Beach Drive to Marion Transit Parking Lotbus bus 100
    2. Take the bus from Tampa Bus Station to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Raleigh Bus Stationbus bus
    4. Take the bus from Raleigh Bus Station to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    24h 11m
    $157–281

  4. Train, bus, drive

    1. Take the train from Tampa to Carytrain train
    2. Take the train from Cary to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    24h 45m
    $342–673

  5. Drive 643.8 mi

    1. Drive from St. Petersburg to Great Smoky Mountainscar car 643.8 mi
    12h
    $118–170

  6. Fly Saint Petersburg–Clearwater International Airport to Mcghee Tyson Airport, drive

    1. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Mcghee Tyson Airport (TYS)plane plane PIE - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    5h 52m
    $135–721

  7. Fly Tampa to Greenville–Spartanburg International Airport, drive

    1. Fly from Tampa (TPA) to Greenville–Spartanburg International Airport (GSP)plane plane TPA - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Great Smoky Mountainscar car
    8h 19m
    $104–260

Sarasota–Bradenton International Airport (SRQ) to Mcghee Tyson Airport (TYS) flights

Calendar22Weekly Planes
Duration3h 32mAverage Duration
Ticket$186Cheapest Price
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Questions & Answers

Map of how to get from St. Petersburg to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 682.8 mi
  • Duration: 6h 15m

What companies run services between St. Petersburg, FL, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from St. Petersburg to Great Smoky Mountains. However, you can take the bus to Desoto Station Parking For 12 & 203, walk to 301 Blvd W @ 9Th St Ext Ns, take the bus to Airport Cir @ Bradenton Connector Ns, walk to Sarasota–Bradenton International Airport (SRQ) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from 2Nd Ave Ne + Beach Drive to Great Smoky Mountains via Marion Transit Parking Lot, Tampa Bus Station, Orlando Bus Station, Raleigh Bus Station, and Asheville, NC in around 24h 11m.

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