What is the cheapest way to get from St. Petersburg to Key Largo?

The cheapest way to get from St. Petersburg to Key Largo is to drive which costs $50 - $80 and takes 5h 19m.

What is the fastest way to get from St. Petersburg to Key Largo?

The fastest way to get from St. Petersburg to Key Largo is to drive which takes 5h 19m and costs $50 - $80.

Is there a direct bus between St. Petersburg and Key Largo?

No, there is no direct bus from St. Petersburg to Key Largo. However, there are services departing from 2Nd Ave Ne + Beach Drive and arriving at Key Largo Bus Stop via Tampa Bus Station and Miami Airport Station. The journey, including transfers, takes approximately 10h 38m.

How far is it from St. Petersburg to Key Largo?

The distance between St. Petersburg and Key Largo is 340 miles. The road distance is 288.5 miles.

How do I travel from St. Petersburg to Key Largo without a car?

The best way to get from St. Petersburg to Key Largo without a car is to train and bus which takes 8h 57m and costs $140 - $240.

How long does it take to get from St. Petersburg to Key Largo?

It takes approximately 8h 57m to get from St. Petersburg to Key Largo, including transfers.

Where do I catch the St. Petersburg to Key Largo bus from?

St. Petersburg to Key Largo bus services, operated by Pinellas Suncoast Transit Authority, depart from 2Nd Ave Ne + Beach Drive station.

Where does the St. Petersburg to Key Largo bus arrive?

St. Petersburg to Key Largo bus services, operated by Pinellas Suncoast Transit Authority, arrive at Marion Transit Parking Lot station.

Can I drive from St. Petersburg to Key Largo?

Yes, the driving distance between St. Petersburg to Key Largo is 289 miles. It takes approximately 5h 19m to drive from St. Petersburg to Key Largo.

Where can I stay near Key Largo?

There are 260+ hotels available in Key Largo.

St. Petersburg to Key Largo - 9 ways to travel via train, bus, car, and plane

There are 9 ways to get from St. Petersburg to Key Largo by train, bus, bus (Flixbus, Greyhound), car, plane, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Train, bus
best
1. Take the train from Tampa to Delray Beach Amtraktrain
2. Take the train from Delray Beach Station to Miami Airport Stationtrain
3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus
8h 57m
$141–239
Drive 286.9 mi
cheapest
1. Drive from St. Petersburg to Key Largocar 286.9 mi
5h 19m
$53–76
Bus
1. Take the bus from 2Nd Ave Ne + Beach Drive to Marion Transit Parking Lotbus 100
2. Take the bus from Tampa Bus Station to Miami Airport Stationbus
3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus
10h 38m
$56–109
Bus to Sarasota–Bradenton International Airport, fly to Miami International Airport, shuttle
1. Take the bus from Psta Grand Central Station to Desoto Station Parking For 12 & 203bus
2. Fly from Sarasota–Bradenton International Airport (SRQ) to Miami International Airport (MIA)plane SRQ - MIA
3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle
5h 58m
$145–481
Bus, train
1. Take the bus from Tampa Bus Station to Ft Lauderdale Broward Park & Ridebus
2. Take the train from Fort Lauderdale Station to Miami Airport Stationtrain
3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus
14h 57m
$58–113
Fly Tampa to Miami International Airport, shuttle
1. Fly from Tampa (TPA) to Miami International Airport (MIA)plane TPA - MIA
2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle
6h 53m
$855–1,235
Fly Tampa to Fort Lauderdale–Hollywood International Airport, shuttle
1. Fly from Tampa (TPA) to Fort Lauderdale–Hollywood International Airport (FLL)plane TPA - FLL
2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle
7h 18m
$235–705
Fly Saint Petersburg–Clearwater International Airport to Key West International Airport, bus
1. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane PIE - EYW
2. Take the bus from Key West Airport to Key Largo Bus Stopbus
7h 14m
$55–274
Fly Tampa to Key West International Airport, bus
1. Fly from Tampa (TPA) to Key West International Airport (EYW)plane TPA - EYW
2. Take the bus from Key West Airport to Key Largo Bus Stopbus
8h 37m
$90–424

St. Petersburg to Key Largo by bus

19Weekly Buses

10h 38mAverage Duration

$56Cheapest Price

See schedules

Questions & Answers

Map of how to get from St. Petersburg to Key Largo.

Launch map view

Distance: 337.9 mi
Duration: 8h 57m

What companies run services between St. Petersburg, FL, USA and Key Largo, FL, USA?

You can take a bus from 2Nd Ave Ne + Beach Drive to Key Largo Bus Stop via Marion Transit Parking Lot, Tampa Bus Station, and Miami Airport Station in around 10h 38m.

Airlines

Train operators

Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.