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How to get fromSt. Petersburg to Key Largoby train, bus, bus (Greyhound), car, plane, shuttle, or bus (Flixbus, Greyhound)

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There are 9 ways to get from St. Petersburg to Key Largo by train, bus, bus (Greyhound), car, plane, shuttle, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Tampa to Delray Beach Amtraktrain train
    2. Take the train from Delray Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    8h 57m
    $130–228

  2. Fly Saint Petersburg–Clearwater International Airport to Key West International Airport, bus

    cheapest
    1. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane plane PIE - EYW
    2. Take the bus from Key West Airport to Key Largo Bus Stopbus bus
    7h 13m
    $48–272

  3. Bus via Fruitville

    1. Take the bus from Psta Grand Central Station to Desoto Station Parking For 12 & 203bus bus 203
    2. Take the bus from Bradenton/Sarasota - Mobil Gas Station to Miami Airportbus bus
    3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    10h 31m
    $58–141

  4. Drive 286.9 mi

    1. Drive from St. Petersburg to Key Largocar car 286.9 mi
    5h 19m
    $53–76

  5. Bus to Sarasota–Bradenton International Airport, fly to Miami International Airport, shuttle

    1. Take the bus from Psta Grand Central Station to Desoto Station Parking For 12 & 203bus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Miami International Airport (MIA)plane plane SRQ - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    5h 56m
    $155–561

  6. Bus

    1. Take the bus from Tampa Bus Station to Miami Airport Stationbus bus FlixBus 2421 / ...
    2. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus Greyhound US0720s
    12h 33m
    $53–101

  7. Fly Tampa to Miami International Airport, shuttle

    1. Fly from Tampa (TPA) to Miami International Airport (MIA)plane plane TPA - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    6h 50m
    $755–1,235

  8. Fly Tampa to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Tampa (TPA) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane TPA - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    7h 19m
    $225–655

  9. Fly Tampa to Key West International Airport, bus

    1. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    2. Take the bus from Key West Airport to Key Largo Bus Stopbus bus
    8h 33m
    $83–422

St. Petersburg to Key Largo by bus and tram

Calendar7Weekly Services
Duration10h 31mAverage Duration
Ticket$58Cheapest Price
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Questions & Answers

Map of how to get from St. Petersburg to Key Largo.ExpandLaunch map view
  • Distance: 337.9 mi
  • Duration: 8h 57m

What companies run services between St. Petersburg, FL, USA and Key Largo, FL, USA?

You can take a bus from Psta Grand Central Station to Key Largo Bus Stop via Desoto Station Parking For 12 & 203, 301 Blvd W @ 9Th St Ext Ns, Downtown Transfer Station, Cattlemen Rd @ Fruitville Rd, Bradenton/Sarasota - Mobil Gas Station, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, and Miami Airport Station in around 10h 31m.

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