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How to get fromSt. Petersburg to Key West, FLby bus, plane, ferry, train, shuttle, car, or bus (Flixbus, Greyhound)

Find Transport to Key West, FL

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There are 9 ways to get from St. Petersburg to Key West, FL by bus, plane, ferry, train, shuttle, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 11 bus to Saint Petersburg–Clearwater International Airport, fly

    best
    1. Take the bus from Grand Central Station - A to Psta 34Th St Complex - Shelter - Bbus bus
    2. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane plane PIE - EYW
    4h 39m
    $115–335

  2. Bus

    cheapest
    1. Take the bus from 2Nd Ave Ne + Beach Drive to Marion Transit Parking Lotbus bus 100
    2. Take the bus from Tampa Bus Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to Whitehead & Eatonbus bus Lks
    15h 42m
    $69–136

  3. Bus, ferry via Bradenton

    1. Take the bus from Bradenton to Fort Myersbus bus Houston
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry Fort Myers Beach
    10h 11m
    $225–260

  4. Train, bus, shuttle

    1. Take the train from Tampa to Delray Beach Amtraktrain train
    2. Take the train from Delray Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take a shuttle bus from Big Pine Key, FL to Key West, FLshuttle bus
    12h 47m
    $242–372

  5. Bus, shuttle

    1. Take the bus from Psta Grand Central Station to Desoto Station Parking For 12 & 203bus bus 203
    2. Take the bus from Bradenton/Sarasota - Mobil Gas Station to Miami Airportbus bus
    3. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    13h 5m
    $225–325

  6. Line 11 bus to Tampa, fly

    1. Take the bus from Grand Central Station - A to Psta 34Th St Complex - Shelter - Bbus bus
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    6h 2m
    $150–485

  7. Drive to Orlando Sanford, fly

    1. Drive from St. Petersburg to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    4h 56m
    $133–373

  8. Bus, ferry

    1. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus FlixBus 2421
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry Fort Myers Beach
    13h 27m
    $191–218

  9. Drive 385.5 mi

    1. Drive from St. Petersburg to Key West, FLcar car 385.5 mi
    7h 39m
    $71–102

St. Petersburg to Key West, FL by bus and shuttle

Calendar10Weekly Services
Duration13h 5mAverage Duration
Ticket$225Cheapest Price
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Questions & Answers

Map of how to get from St. Petersburg to Key West, FL.ExpandLaunch map view
  • Distance: 257.1 mi
  • Duration: 4h 39m

What companies run services between St. Petersburg, FL, USA and Key West, FL, USA?

You can take a bus from 2Nd Ave Ne + Beach Drive to Whitehead & Eaton via Marion Transit Parking Lot, Tampa Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 15h 42m.

Airlines
Train operators
Bus operators
Ferry operators

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