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How to get fromSt. Petersburg to Mayo Clinic Hospitalby bus, plane, bus (Flixbus, Greyhound), train, or car

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There are 8 ways to get from St. Petersburg to Mayo Clinic Hospital by bus, plane, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Sarasota–Bradenton International Airport, fly to Rochester

    best
    1. Take the bus from Psta Grand Central Station to Desoto Station Parking For 12 & 203bus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Rochester (RST)plane plane SRQ - RST
    9h 48m
    $151–751

  2. Fly Tampa to Rochester

    cheapest
    1. Fly from Tampa (TPA) to Rochester (RST)plane plane TPA - RST
    10h 17m
    $126–595

  3. Bus

    1. Take the bus from 2Nd Ave Ne + Beach Drive to Marion Transit Parking Lotbus bus 100
    2. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    5. Take the bus from Milwaukee to Rochesterbus bus
    37h 23m
    $255–468

  4. Train, bus

    1. Take the train from Tampa to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochesterbus bus
    2d 4h
    $770–1,583

  5. Drive 1,478.5 mi

    1. Drive from St. Petersburg to Mayo Clinic Hospitalcar car 1,478.5 mi
    25h 8m
    $270–390

  6. Fly Tampa to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Tampa (TPA) to Minneapolis–Saint Paul International Airport (MSP)plane plane TPA - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 42m
    $547–1,157

  7. Bus to Sarasota–Bradenton International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Psta Grand Central Station to Desoto Station Parking For 12 & 203bus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Minneapolis–Saint Paul International Airport (MSP)plane plane SRQ - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 4m
    $232–913

  8. Amtrak Thruway, train, bus

    1. Take the bus from St. Petersburg to Orlando, FLbus bus
    2. Take the train from Orlando to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    2d 7h
    $607–1,382

Sarasota–Bradenton International Airport (SRQ) to Rochester (RST) flights

Calendar13Weekly Planes
Duration7h 12mAverage Duration
Ticket$151Cheapest Price
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Questions & Answers

Map of how to get from St. Petersburg to Mayo Clinic Hospital.ExpandLaunch map view
  • Distance: 1,313.9 mi
  • Duration: 9h 48m

What companies run services between St. Petersburg, FL, USA and Mayo Clinic Hospital, MN, USA?

You can take a bus from 2Nd Ave Ne + Beach Drive to Mayo Clinic Hospital via Marion Transit Parking Lot, Tampa Bus Station, Atlanta Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 37h 23m. Alternatively, American Airlines, Delta, and two other airlines fly from Tampa (TPA) to Rochester (RST) every 4 hours.

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