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How to get fromSt. Petersburg to Orangeburgby train (Amtrak), bus (Flixbus, Greyhound), car, plane, taxi, or bus

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There are 7 ways to get from St. Petersburg to Orangeburg by train (Amtrak), bus (Flixbus, Greyhound), car, plane, taxi, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Tampa to Denmark Amtrak Stationtrain train Floridian
    11h 15m
    $277–473

  2. Bus

    cheapest
    1. Take the bus from 2Nd Ave Ne + Beach Drive to Marion Transit Parking Lotbus bus 100
    2. Take the bus from Tampa Bus Station to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Orangeburgbus bus
    12h 21m
    $82–146

  3. Drive 450.7 mi

    1. Drive from St. Petersburg to Orangeburgcar car 450.7 mi
    8h 15m
    $83–119

  4. Fly Tampa to Columbia, taxi

    1. Fly from Tampa (TPA) to Columbia (CAE)plane plane TPA - CAE
    2. Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi taxi
    7h 28m
    $305–1,155

  5. Fly Tampa to Myrtle Beach, bus

    1. Fly from Tampa (TPA) to Myrtle Beach (MYR)plane plane TPA - MYR
    2. Take the bus from Myrtle Beach Bus Station to Orangeburgbus bus
    10h 5m
    $124–339

  6. Bus to Sarasota–Bradenton International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Psta Grand Central Station to Desoto Station Parking For 12 & 203bus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Charlotte Douglas International Airport (CLT)plane plane SRQ - CLT
    3. Take the bus from Charlotte Bus Station to Orangeburgbus bus
    10h 28m
    $157–777

  7. Line 11 bus, line 300 bus to Tampa, fly to Charleston International Airport, line 104 bus, bus

    1. Take the bus from Grand Central Station - A to Psta 34Th St Complex - Shelter - Bbus bus
    2. Take the bus from Psta 34Th St Layby - Platform - D to TPA RENTAL CAR FACILITY westboundbus bus
    3. Fly from Tampa (TPA) to Charleston International Airport (CHS)plane plane TPA - CHS
    4. Take the bus from N. Charleston SuperStop to North Charleston Transit Centerbus bus
    5. Take the bus from Charleston Bus Station to Orangeburgbus bus
    9h 31m
    $167–379

Tampa (TPA) to Columbia (CAE) flights

Calendar106Weekly Planes
Duration4h 21mAverage Duration
Ticket$181Cheapest Price
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Questions & Answers

Map of how to get from St. Petersburg to Orangeburg.ExpandLaunch map view
  • Distance: 516.9 mi
  • Duration: 11h 15m

What companies run services between St. Petersburg, FL, USA and Orangeburg, SC, USA?

Amtrak operates a train from Tampa to Denmark Amtrak Station once daily. Tickets cost $150–320 and the journey takes 10h 13m. Alternatively, you can take a bus from 2Nd Ave Ne + Beach Drive to Orangeburg via Marion Transit Parking Lot, Tampa Bus Station, Orlando Bus Station, and Orangeburg in around 12h 21m.

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