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How to get fromSt. Petersburg to St. Louisby bus, plane, bus (Flixbus, Greyhound), car, or bus (Greyhound)

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There are 5 ways to get from St. Petersburg to St. Louis by bus, plane, bus (Flixbus, Greyhound), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Sarasota–Bradenton International Airport, fly

    best
    1. Take the bus from Psta Grand Central Station to Desoto Station Parking For 12 & 203bus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Lambert–St. Louis International Airport (STL)plane plane SRQ - STL
    5h 43m
    $163–814

  2. Bus

    cheapest
    1. Take the bus from 2Nd Ave Ne + Beach Drive to Marion Transit Parking Lotbus bus 100
    2. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    22h 28m
    $162–302

  3. Drive 1,029.6 mi

    1. Drive from St. Petersburg to St. Louiscar car 1,029.6 mi
    17h 1m
    $188–272

  4. Line 11 bus, line 300 bus to Tampa, fly

    1. Take the bus from Grand Central Station - A to Psta 34Th St Complex - Shelter - Bbus bus
    2. Take the bus from Psta 34Th St Layby - Platform - D to TPA RENTAL CAR FACILITY westboundbus bus
    3. Fly from Tampa (TPA) to Lambert–St. Louis International Airport (STL)plane plane TPA - STL
    6h 32m
    $428–2,008

  5. Bus via Nashville

    1. Take the bus from Tampa Bus Station to Tallahasseebus bus
    2. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Evansville Bus Stationbus bus
    4. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    28h 38m
    $260–380

St. Petersburg to St. Louis by bus

Calendar7Weekly Buses
Duration22h 28mAverage Duration
Ticket$162Cheapest Price
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Questions & Answers

Map of how to get from St. Petersburg to St. Louis.ExpandLaunch map view
  • Distance: 954.4 mi
  • Duration: 5h 43m

What companies run services between St. Petersburg, FL, USA and St. Louis, MO, USA?

You can take a bus from 2Nd Ave Ne + Beach Drive to St Louis Bus Station via Marion Transit Parking Lot, Tampa Bus Station, and Atlanta Bus Station in around 22h 28m.

Airlines
Bus operators

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