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How to get fromSt. Petersburg to Winston-Salemby bus, plane, bus (Flixbus, Greyhound), train, or car

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There are 9 ways to get from St. Petersburg to Winston-Salem by bus, plane, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Sarasota–Bradenton International Airport, fly to Charlotte Douglas International Airport, bus

    best
    1. Take the bus from Psta Grand Central Station to Desoto Station Parking For 12 & 203bus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Charlotte Douglas International Airport (CLT)plane plane SRQ - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    7h 50m
    $131–757

  2. Fly Saint Petersburg–Clearwater International Airport to Asheville Regional Airport, bus

    cheapest
    1. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Asheville Regional Airport (AVL)plane plane PIE - AVL
    2. Take the bus from Asheville, NC to Winston Salem(Trans Center)bus bus
    9h 1m
    $88–401

  3. Bus

    1. Take the bus from 2Nd Ave Ne + Beach Drive to Marion Transit Parking Lotbus bus 100
    2. Take the bus from Tampa Bus Station to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    17h 23m
    $101–206

  4. Train, bus

    1. Take the train from Tampa to Carytrain train
    2. Take the train from Cary to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    19h 56m
    $319–611

  5. Drive 669.5 mi

    1. Drive from St. Petersburg to Winston-Salemcar car 669.5 mi
    11h 32m
    $123–177

  6. Line 11 bus to Saint Petersburg–Clearwater International Airport, fly to Piedmont Triad International Airport

    1. Take the bus from Grand Central Station - A to Psta 34Th St Complex - Shelter - Bbus bus
    2. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Piedmont Triad International Airport (GSO)plane plane PIE - GSO
    5h 11m
    $134–628

  7. Fly Tampa to Charlotte Douglas International Airport, bus

    1. Fly from Tampa (TPA) to Charlotte Douglas International Airport (CLT)plane plane TPA - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    8h 33m
    $111–601

  8. Line 11 bus, line 300 bus to Tampa, fly to Raleigh-Durham International Airport, line 700 bus, bus

    1. Take the bus from Grand Central Station - A to Psta 34Th St Complex - Shelter - Bbus bus
    2. Take the bus from Psta 34Th St Layby - Platform - D to TPA RENTAL CAR FACILITY westboundbus bus
    3. Fly from Tampa (TPA) to Raleigh-Durham International Airport (RDU)plane plane TPA - RDU
    4. Take the bus from Regional Transit Center to Durham Stationbus bus
    5. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    9h 20m
    $108–444

  9. Line 11 bus to Saint Petersburg–Clearwater International Airport, fly to Concord, train, bus

    1. Take the bus from Grand Central Station - A to Psta 34Th St Complex - Shelter - Bbus bus
    2. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Concord (USA)plane plane PIE - USA
    3. Take the train from Kannapolis to High Pointtrain train
    4. Take the bus from High Point Terminal to Winston-Salem Transportation Centerbus bus
    7h 52m
    $103–290

St. Petersburg to Winston-Salem by bus

Calendar7Weekly Buses
Duration17h 23mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

Map of how to get from St. Petersburg to Winston-Salem.ExpandLaunch map view
  • Distance: 670.2 mi
  • Duration: 7h 50m

What companies run services between St. Petersburg, FL, USA and Winston-Salem, NC, USA?

You can take a bus from 2Nd Ave Ne + Beach Drive to Winston Salem(Trans Center) via Marion Transit Parking Lot, Tampa Bus Station, Orlando Bus Station, and Charlotte Bus Station in around 17h 23m.

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