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How to get fromState College to Knoxvilleby plane, bus (Greyhound), car, bus, train, or bus (Flixbus)

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There are 6 ways to get from State College to Knoxville by plane, bus (Greyhound), car, bus, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Penn State University Park Airport

    best
    1. Fly from Penn State University Park Airport (SCE) to Mcghee Tyson Airport (TYS)plane plane SCE - TYS
    5h 26m
    $189–739

  2. Drive 558.5 mi

    cheapest
    1. Drive from State College to Knoxvillecar car 558.5 mi
    10h 23m
    $102–148

  3. Bus via Farragut

    1. Take the bus from State College, Pa to Port Authority Bus Terminalbus bus Pittsburgh
    2. Take the bus from New York to Knoxvillebus bus Nyc
    18h 37m
    $221–348

  4. Bus to Harrisburg International Airport, fly

    1. Take the bus from State College Bus Station to Harrisburg Bus Stationbus bus
    2. Fly from Harrisburg International Airport (MDT) to Mcghee Tyson Airport (TYS)plane plane MDT - TYS
    8h 1m
    $300–1,399

  5. Bus, train

    1. Take the bus from State College Bus Station to Harrisburg Bus Stationbus bus
    2. Take the train from Harrisburg to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    19h 56m
    $212–320

  6. Bus

    1. Take the bus from State College Regional Airport to New York City Chinatownbus bus FlixBus N2640
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    24h 45m
    $163–219

Penn State University Park Airport (SCE) to Mcghee Tyson Airport (TYS) flights

Calendar68Weekly Planes
Duration5h 13mAverage Duration
Ticket$119Cheapest Price
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Questions & Answers

Map of how to get from State College to Knoxville.ExpandLaunch map view
  • Distance: 500.5 mi
  • Duration: 5h 26m

What companies run services between State College, PA, USA and Knoxville, TN, USA?

United Airlines and American Airlines fly from Penn State University Park Airport (SCE) to Mcghee Tyson Airport (TYS) every 3 hours. Alternatively, you can take a bus from State College, Pa to Knoxville via Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 18h 37m.

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