There are 4 ways to get from Strasbourg to Main by train (TGV), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Strasbourg Bahnhof to Mannheim, Hauptbahnhoftrain 82 / ...
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
2h 44m€38–121Bus
cheapest- Take the bus from Strasbourg to Frankfurt Airportbus FlixBus 108 / ...
5h 17m€17–35Drive 191.7 km
- Drive from Strasbourg to Maincar 191.7 km
2h 8m€31–45Train via Karlsruhe
- Take the train from Strasbourg to Karlsruhe Hbftrain Ice / ...
- Take the train from Karlsruhe Hauptbahnhof to Mainz, Hauptbahnhoftrain Re4
3h 16m€36–168
Strasbourg to Main by train
Comparing Your Travel Options
The cheapest way to get from Strasbourg to Main is to bus which costs €17 - €35 and takes 5h 17m.
The fastest way to get from Strasbourg to Main is to drive which takes 2h 8m and costs €30 - €45.
No, there is no direct bus from Strasbourg to Main. However, there are services departing from Strasbourg and arriving at Wiesbaden-Mainz-Kostheim Luisenstraße via Frankfurt and Mainz-Bischofsheim Bahnhof. The journey, including transfers, takes approximately 5h 17m.
No, there is no direct train from Strasbourg to Main. However, there are services departing from Strasbourg Bahnhof and arriving at Mainz, Römisches Theater via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 2h 44m.
The distance between Strasbourg and Main is 210 km. The road distance is 191.7 km.
The best way to get from Strasbourg to Main without a car is to train which takes 2h 44m and costs €35 - €130.
It takes approximately 2h 44m to get from Strasbourg to Main, including transfers.
Strasbourg to Main bus services, operated by FlixBus, depart from Strasbourg station.
Strasbourg to Main train services, operated by Deutsche Bahn Intercity (DB IC), depart from Strasbourg Bahnhof station.
The best way to get from Strasbourg to Main is to train which takes 2h 44m and costs €35 - €130. Alternatively, you can bus, which costs €17 - €35 and takes 5h 17m.
What companies run services between Strasbourg, France and Main, Hesse, Germany?
You can take a train from Strasbourg Bahnhof to Mainz, Römisches Theater via Mannheim, Hauptbahnhof in around 2h 44m. Alternatively, FlixBus operates a bus from Strasbourg to Frankfurt Airport 4 times a day. Tickets cost €20–35 and the journey takes 3h 35m. BlaBlaCar Bus also services this route every 4 hours.
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Strasbourg Bahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 4m
- Frequency
- 4 times a day
- Estimated price
- €24–55
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 39 min
- Frequency
- Every 4 hours
- Estimated price
- €13–29
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 2h 23m
- Frequency
- 3 times a day
- Estimated price
- €23–50
- Website
- Deutsche Bahn Intercity (DB IC)
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- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Strasbourg Bahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 22m
- Frequency
- Twice daily
- Estimated price
- €29–45
- Website
- TGV inOui
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 44 min
- Frequency
- 5 times a day
- Estimated price
- €16–24
- Website
- TGV inOui
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €14–70
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 2h 25m
- Frequency
- Every 4 hours
- Estimated price
- €29–140
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 6 times a week
- Estimated price
- €14–20
- Schedules at
- Süwex
Train from Karlsruhe Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Every 4 hours
- Estimated price
- €23–35
- Schedules at
- Süwex
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact DetailsContact Details
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 49 min
- Frequency
- Twice a week
- Estimated price
- €14–24
- Website
- Oui.SNCF
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Strasbourg to Frankfurt Airport
- Ave. Duration
- 3h 35m
- Frequency
- 4 times a day
- Estimated price
- €20–35
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Strasbourg to Frankfurt Airport
- Ave. Duration
- 3h 55m
- Frequency
- Every 4 hours
- Estimated price
- €17–29
- Website
- BlaBlaCar Bus
Want to know more about travelling around Germany
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Booking & Getting There
Strasbourg to Main bus services, operated by FlixBus, arrive at Frankfurt Airport station.
Strasbourg to Main train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Strasbourg to Main is 192 km. It takes approximately 2h 8m to drive from Strasbourg to Main.
Book your Strasbourg to Main train tickets online with Omio.
There are 1243+ hotels available in Main.