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How to get fromStrasbourg to Sienaby plane, train, train (Trenitalia), bus, or car

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There are 10 ways to get from Strasbourg to Siena by plane, train, train (Trenitalia), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Strasbourg International Airport to Florence Peretola Airport, train

    best
    1. Fly from Strasbourg International Airport (SXB) to Florence Peretola Airport (FLR)plane plane SXB - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    5h 54m
    €89–404

  2. Bus via Milan

    cheapest
    1. Take the bus from Strasbourg - L'Étoile Park Bus Station to Milano, Autostazione Lampugnanobus bus BlaBlaCar Bus
    2. Take the bus from Milano, Autostazione Lampugnano to Sienabus bus N528 / ...
    13h 50m
    €69–118

  3. Train

    1. Take the train from Strasbourg to Basel Sbbtrain train Ter
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Sienatrain train Re
    11h 20m
    €111–494

  4. Bus

    1. Take the bus from Strasbourg to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    13h 34m
    €126–172

  5. Drive  832.5 km

    1. Drive from Strasbourg to Sienacar car 832.5 km
    8h 35m
    €132–190

  6. Train, train to Zurich Airport, fly to Florence Peretola Airport

    1. Take the train from Strasbourg to Basel Sbbtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane plane ZRH - FLR
    4. Take the train from Firenze S.M.N. to Sienatrain train
    8h 23m
    €169–427

  7. Train, train to Frankfurt, fly to Florence Peretola Airport

    1. Take the train from Strasbourg to Mannheim Hbftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    4. Take the train from Firenze S.M.N. to Sienatrain train
    7h 53m
    €166–444

  8. Train, train to Frankfurt, fly to Pisa International Airport

    1. Take the train from Strasbourg to Mannheim Hbftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane plane FRA - PSA
    4. Take the train from Pisa Centrale to Empolitrain train
    5. Take the train from Empoli to Sienatrain train
    7h 46m
    €150–423

  9. Train, train to Frankfurt, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Strasbourg to Mannheim Hbftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    4. Take the train from Bologna Centrale to Firenze S.M.N.train train
    5. Take the train from Firenze S.M.N. to Sienatrain train
    8h 18m
    €149–439

  10. Train, train to Zurich Airport, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Strasbourg to Basel Sbbtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Bologna Guglielmo Marconi Airport (BLQ)plane plane ZRH - BLQ
    4. Take the train from Bologna Centrale to Firenze S.M.N.train train
    5. Take the train from Firenze S.M.N. to Sienatrain train
    8h 53m
    €162–462

Strasbourg to Siena by train

Calendar76Weekly Trains
Duration11h 20mAverage Duration
Ticket€111Cheapest Price
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Questions & Answers

Map of how to get from Strasbourg to Siena.ExpandLaunch map view
  • Distance: 702.1 km
  • Duration: 5h 54m

What companies run services between Strasbourg, France and Siena, Italy?

You can take a train from Strasbourg to Siena via Basel Sbb, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 11h 20m. Alternatively, you can take a bus from Strasbourg to Siena via Florence Villa Constanza Bus Station in around 13h 34m.

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