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How to get fromSumter to Knoxvilleby bus, plane, shuttle, car, or taxi

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There are 7 ways to get from Sumter to Knoxville by bus, plane, shuttle, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Florence Regional Airport, fly to Mcghee Tyson Airport

    best
    1. Take the bus from Sumter Bus Stop to Florence Bus Stationbus bus
    2. Fly from Florence Regional Airport (FLO) to Mcghee Tyson Airport (TYS)plane plane FLO - TYS
    5h 50m
    $153–647

  2. Drive 306.6 mi

    cheapest
    1. Drive from Sumter to Knoxvillecar car 306.6 mi
    5h 35m
    $56–81

  3. Bus, shuttle, drive

    1. Take the bus from Sumter Bus Stop to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Airport to ASU Peacock Hall Boonebus bus
    3. Take a shuttle bus from Boone to Black Bear Resortshuttle bus
    4. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    5. Drive from Hot Springs to Knoxvillecar car
    11h 57m
    $347–391

  4. Bus to Charlotte Douglas International Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Sumter Bus Stop to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Mcghee Tyson Airport (TYS)plane plane CLT - TYS
    5h 52m
    $162–759

  5. Bus to Columbia, fly to Mcghee Tyson Airport

    1. Take the bus from James E Clyburn Intermodal Transportation Center to Laurel Sumter Eastbus bus
    2. Fly from Columbia (CAE) to Mcghee Tyson Airport (TYS)plane plane CAE - TYS
    7h 15m
    $238–1,374

  6. Bus to Charlotte Douglas International Airport, fly to Asheville Regional Airport, drive

    1. Take the bus from Sumter Bus Stop to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Asheville Regional Airport (AVL)plane plane CLT - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    7h 26m
    $84–404

  7. Bus, taxi, shuttle, drive

    1. Take the bus from Sumter Bus Stop to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Airport to ASU Peacock Hall Boonebus bus
    3. Take the taxi from ASU Peacock Hall Boone to Black Bear Resorttaxi taxi
    4. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    5. Drive from Hot Springs to Chilhowee at Holstoncar car
    12h 12m
    $382–456

Florence Regional Airport (FLO) to Mcghee Tyson Airport (TYS) flights

Calendar8Weekly Planes
Duration3h 58mAverage Duration
Ticket$82Cheapest Price
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Questions & Answers

Map of how to get from Sumter to Knoxville.ExpandLaunch map view
  • Distance: 320.7 mi
  • Duration: 5h 50m

What companies run services between Sumter, SC, USA and Knoxville, TN, USA?

There is no direct connection from Sumter to Knoxville. However, you can take the bus to Florence Bus Station, take the taxi to Florence Regional Airport (FLO) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take a bus from Sumter Bus Stop to Knoxville via Charlotte Bus Station, Trade St & Graham St, Transit Center- Bay A, Transit Center- Bay V, Charlotte Douglas Airport, Charlotte Airport, ASU Peacock Hall Boone, Boone, Black Bear Resort, and Hot Springs in around 11h 57m.

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