There are 6 ways to get from Sumter to Knoxville by bus, plane, shuttle, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Charlotte Douglas International Airport, fly to Mcghee Tyson Airport
best- Take the bus from Sumter Bus Stop to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Mcghee Tyson Airport (TYS)plane CLT - TYS
5h 41m$171–803Drive 306.6 mi
cheapest- Drive from Sumter to Knoxvillecar 306.6 mi
5h 35m$56–81Bus, shuttle, drive
- Take the bus from Sumter Bus Stop to Charlotte Bus Stationbus
- Take the bus from Charlotte to Boonebus
- Take a shuttle bus from Boone to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Hot Springs
- Drive from Hot Springs to Knoxvillecar
11h 59m$269–293Bus to Columbia, fly to Mcghee Tyson Airport
- Take the bus from James E Clyburn Intermodal Transportation Center to Laurel Sumter Eastbus
- Fly from Columbia (CAE) to Mcghee Tyson Airport (TYS)plane CAE - TYS
7h 28m$158–774Bus, bus to Florence Regional Airport, fly to Mcghee Tyson Airport
- Take the bus from Sumter Bus Stop to Camdenbus
- Take the bus from Camden to Florence Bus Stationbus
- Fly from Florence Regional Airport (FLO) to Mcghee Tyson Airport (TYS)plane FLO - TYS
7h 30m$179–855Bus to Charlotte Douglas International Airport, fly to Asheville Regional Airport, drive
- Take the bus from Sumter Bus Stop to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Asheville Regional Airport (AVL)plane CLT - AVL
- Drive from Asheville-Airport-AVL to Knoxvillecar
7h 22m$78–368
Charlotte Douglas International Airport (CLT) to Mcghee Tyson Airport (TYS) flights
Comparing Your Travel Options
The cheapest way to get from Sumter to Knoxville is to drive which costs $55 - $85 and takes 5h 35m.
The fastest way to get from Sumter to Knoxville is to drive which takes 5h 35m and costs $55 - $85.
The distance between Sumter and Knoxville is 305 miles. The road distance is 308.3 miles.
It takes approximately 5h 41m to get from Sumter to Knoxville, including transfers.
Yes, the driving distance between Sumter to Knoxville is 308 miles. It takes approximately 5h 35m to drive from Sumter to Knoxville.
There are 325+ hotels available in Knoxville.
What companies run services between Sumter, SC, USA and Knoxville, TN, USA?
There is no direct connection from Sumter to Knoxville. However, you can take the bus to Charlotte Bus Station, walk to Trade St & Graham St, take the line 34 bus to Transit Center- Bay A, walk to Transit Center- Bay V, take the line 5 bus to Charlotte Douglas Airport, walk to Charlotte Douglas International Airport (CLT) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take a bus from Sumter Bus Stop to Knoxville via Charlotte, Boone, Boone, Black Bear Resort, and Hot Springs in around 11h 59m.
- Website
- aa.com
Flights from Charlotte Douglas International Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $95–700
Flights from Columbia to Mcghee Tyson Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $100–700
Flights from Columbia to Mcghee Tyson Airport via Philadelphia
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Columbia to Mcghee Tyson Airport via Miami
- Ave. Duration
- 6h 9m
- When
- Saturday
- Estimated price
- $240–1,200
Flights from Columbia to Mcghee Tyson Airport via New York La Guardia
- Ave. Duration
- 7h 3m
- When
- Saturday
- Estimated price
- $240–1,200
Flights from Florence Regional Airport to Mcghee Tyson Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $100–750
Flights from Charlotte Douglas International Airport to Asheville Regional Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- $35–300
- Website
- delta.com
Flights from Charlotte Douglas International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 9m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–800
Flights from Columbia to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $110–750
Flights from Columbia to Mcghee Tyson Airport via New York La Guardia
- Ave. Duration
- 5h 51m
- When
- Saturday
- Estimated price
- $240–1,200
- Website
- united.com
Flights from Columbia to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $180–950
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Sumter Bus Stop to Charlotte Bus Station
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $17–27
- Website
- Greyhound
Bus from Sumter Bus Stop to Charlotte Bus Station
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $17–27
- Website
- Greyhound
Bus from Sumter Bus Stop to Camden
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $4–7
- Website
- Greyhound
Bus from Camden to Florence Bus Station
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $8–13
- Website
- Greyhound
Bus from Sumter Bus Stop to Charlotte Bus Station
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $17–27
- Website
- Greyhound
- Phone
- +1 704-348-1200
- [email protected]
- Website
- Sunway Charters
Bus from Charlotte to Boone
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $17–24
- Schedules at
- Sunway Charters
- Passenger
- $17–24
- Phone
- +1-423-725-5988
- Website
- Black Bear Resort Shuttle
Shuttle from Boone to Black Bear Resort
- Ave. Duration
- 1h
- Frequency
- On demand
- Estimated price
- $86
- Website
- Black Bear Resort Shuttle
Shuttle from Black Bear Resort to Hot Springs
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- Black Bear Resort Shuttle
- Phone
- +1 803-255-7100
- Website
- The COMET
Bus from James E Clyburn Intermodal Transportation Center to Laurel Sumter East
- Ave. Duration
- 1h 27m
- Frequency
- Once daily
- Estimated price
- $2
- Schedules at
- The COMET
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