Rome2Rio

How to get fromSumter to Louisvilleby car, plane, bus (Greyhound, Flixbus, Amtrak), bus, or bus (Greyhound, Flixbus)

Find Transport to Louisville

See all options

There are 8 ways to get from Sumter to Louisville by car, plane, bus (Greyhound, Flixbus, Amtrak), bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Charleston International Airport, fly to Louisville International Airport

    best
    1. Drive from Sumter to Charleston-Airport-CHScar car
    2. Fly from Charleston International Airport (CHS) to Louisville International Airport (SDF)plane plane CHS - SDF
    4h 50m
    $138–778

  2. Bus to Charlotte Douglas International Airport, fly to Blue Grass Airport, drive

    cheapest
    1. Take the bus from Sumter Bus Stop to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Blue Grass Airport (LEX)plane plane CLT - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    6h 57m
    $86–403

  3. Bus

    1. Take the bus from Sumter Bus Stop to Camdenbus bus
    2. Take the bus from Camden to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    4. Take the bus from Nashville to Louisville, KYbus bus
    16h 50m
    $115–197

  4. Drive  515.1 mi

    1. Drive from Sumter to Louisvillecar car 515.1 mi
    10h 30m
    $94–136

  5. Bus to Charlotte Douglas International Airport, fly to Louisville International Airport

    1. Take the bus from Sumter Bus Stop to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF)plane plane CLT - SDF
    6h 50m
    $119–687

  6. Bus to Columbia, fly to Louisville International Airport

    1. Take the bus from James E Clyburn Intermodal Transportation Center to Laurel Sumter Eastbus bus
    2. Fly from Columbia (CAE) to Louisville International Airport (SDF)plane plane CAE - SDF
    8h 24m
    $104–656

  7. Bus, bus to Florence Regional Airport, fly to Louisville International Airport

    1. Take the bus from Sumter Bus Stop to Camdenbus bus
    2. Take the bus from Camden to Florence Bus Stationbus bus
    3. Fly from Florence Regional Airport (FLO) to Louisville International Airport (SDF)plane plane FLO - SDF
    9h 55m
    $126–688

  8. Bus via Preston @ Vim

    1. Take the bus from Sumter Bus Stop to Camdenbus bus
    2. Take the bus from Camden to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    4. Take the bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KYbus bus
    17h 41m
    $123–212

Sumter to Louisville by bus

Calendar7Weekly Buses
Duration16h 50mAverage Duration
Ticket$115Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Sumter to Louisville.ExpandLaunch map view
  • Distance: 586.5 mi
  • Duration: 4h 50m

What companies run services between Sumter, SC, USA and Louisville, KY, USA?

You can take a bus from Sumter Bus Stop to Louisville, KY via Camden, Atlanta Bus Station, and Nashville in around 16h 50m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound