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How to get fromSumter to St. Louisby car, plane, bus (Greyhound, Flixbus), or bus

Find Transport to St. Louis

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There are 5 ways to get from Sumter to St. Louis by car, plane, bus (Greyhound, Flixbus), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Charleston International Airport, fly

    best
    1. Drive from Sumter to Charleston-Airport-CHScar car
    2. Fly from Charleston International Airport (CHS) to Lambert–St. Louis International Airport (STL)plane plane CHS - STL
    4h 34m
    $130–628
  2. Bus to Columbia, fly

    cheapest
    1. Take the bus from James E Clyburn Intermodal Transportation Center to Laurel Sumter Eastbus bus
    2. Fly from Columbia (CAE) to Lambert–St. Louis International Airport (STL)plane plane CAE - STL
    8h 24m
    $102–556
  3. Bus

    1. Take the bus from Sumter Bus Stop to Camdenbus bus
    2. Take the bus from Camden to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    18h 16m
    $135–227
  4. Drive  786.6 mi

    1. Drive from Sumter to St. Louiscar car 786.6 mi
    13h 31m
    $144–208
  5. Bus to Charlotte Douglas International Airport, fly

    1. Take the bus from Sumter Bus Stop to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)plane plane CLT - STL
    6h 51m
    $121–587

Sumter to St. Louis by bus

Calendar7Weekly Buses
Duration18h 16mAverage Duration
Ticket$135Cheapest Price
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Comparing Your Travel Options

What companies run services between Sumter, SC, USA and St. Louis, MO, USA?

You can take a bus from Sumter Bus Stop to St Louis Bus Station via Camden and Atlanta Bus Station in around 18h 16m.

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