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How to get fromSyracuse Airport (SYR) to Chicagoby plane, train (Amtrak), bus (Greyhound), or car

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There are 5 ways to get from Syracuse Airport (SYR) to Chicago by plane, train (Amtrak), bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Chicago O'Hare International Airport

    best
    1. Fly from Syracuse Hancock International Airport (SYR) to Chicago O'Hare International Airport (ORD)plane plane SYR - ORD
    3h 2m
    $80–419
  2. Train (Amtrak)

    1. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train Lake Shore Limited
    14h 17m
    $213–467
  3. Bus (Greyhound)

    1. Take the bus from Syracuse Bus Station to Cleveland Bus Stationbus bus Greyhound US0171
    2. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    16h 20m
    $103–237
  4. Drive 676.2 mi

    1. Drive from Syracuse Airport (SYR) to Chicagocar car 676.2 mi
    11h 33m
    $124–179
  5. Fly to Chicago Midway International Airport

    1. Fly from Syracuse Hancock International Airport (SYR) to Chicago Midway International Airport (MDW)plane plane SYR - MDW
    4h 38m
    $94–491

Syracuse Airport (SYR) to Chicago by bus and train (Amtrak)

Calendar11Weekly Services
Duration14h 17mAverage Duration
Ticket$213Cheapest Price
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Questions & Answers

What companies run services between Syracuse Airport (SYR), USA and Chicago, IL, USA?

American Airlines, United Airlines, and Delta fly from Syracuse Hancock International Airport (SYR) to Chicago O'Hare International Airport (ORD) hourly. Alternatively, Amtrak operates a train from Syracuse Regional Transportation Center to Chicago Union Station twice daily. Tickets cost $210–440 and the journey takes 13h 7m.

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