There are 12 ways to get from Syracuse to Milan by bus, plane, train, ferry, car, car ferry, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Catania–Fontanarossa Airport, fly to Milan Linate Airport
best- Take the bus from Siracusa - Von Platen to Catania Airportbus
- Fly from Catania–Fontanarossa Airport (CTA) to Milan Linate Airport (LIN)plane CTA - LIN
4h 13m€49–191Bus to Catania–Fontanarossa Airport, fly to Milano Malpensa Airport, train
cheapest- Take the bus from Siracusa - Von Platen to Catania Airportbus
- Fly from Catania–Fontanarossa Airport (CTA) to Milano Malpensa Airport (MXP)plane CTA - MXP
- Take the train from Malpensa Aeroporto T1 to Milano Porta Garibalditrain
5h 2m€24–184Train, ferry
- Take the train from Siracusa to Messina Centraletrain Re
- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Milano Centraletrain Fr
13h 15mBus
- Take the bus from Siracusa - Von Platen to Catania Via Archimedebus Siracusa
- Take the bus from Catania Central Bus Station to Milano - Famagostabus
20h 3m€173–249Drive, car ferry
- Drive from Syracuse to Port of Palermocar
- Take the carferry from Port of Palermo to Port of Genoacarferry
- Drive from Port of Genoa to Milancar
25h 10m€163–245Bus to Catania–Fontanarossa Airport, fly to Il Caravaggio International Airport, bus
- Take the bus from Siracusa - Von Platen to Catania Airportbus
- Fly from Catania–Fontanarossa Airport (CTA) to Il Caravaggio International Airport (BGY)plane CTA - BGY
- Take the bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoiabus
5h 4m€43–251Train to Vincenzo Magliocco Airport, fly to Milan Linate Airport
- Take the train from Siracusa to Comisotrain
- Fly from Vincenzo Magliocco Airport (CIY) to Milan Linate Airport (LIN)plane CIY - LIN
5h 54m€116–592Bus to Catania–Fontanarossa Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the bus from Siracusa - Von Platen to Catania Airportbus
- Fly from Catania–Fontanarossa Airport (CTA) to Bologna Guglielmo Marconi Airport (BLQ)plane CTA - BLQ
- Take the train from Bologna Centrale to Milano Rogoredotrain
5h 18m€42–283Bus to Catania–Fontanarossa Airport, fly to Verona Villafranca Airport, train
- Take the bus from Siracusa - Von Platen to Catania Airportbus
- Fly from Catania–Fontanarossa Airport (CTA) to Verona Villafranca Airport (VRN)plane CTA - VRN
- Take the train from Verona Porta Nuova to Milano Centraletrain
5h 58m€50–320Bus to Catania–Fontanarossa Airport, fly to Turin Caselle Airport, train
- Take the bus from Siracusa - Von Platen to Catania Airportbus
- Fly from Catania–Fontanarossa Airport (CTA) to Turin Caselle Airport (TRN)plane CTA - TRN
- Take the train from Torino Porta Susa to Milano Rogoredotrain
6h 25m€41–236Bus via Milano, San Donato M3
- Take the bus from Siracusa - Von Platen to Catania Airportbus Siracusa
- Take the bus from Catania Airport to Milano, San Donato M3bus N528
22h 49m€113–188Night train
- Take the nighttrain from Siracusa to Milano Centralenighttrain Ini
20h 35m€120–210
Catania–Fontanarossa Airport (CTA) to Milan Linate Airport (LIN) flights
Comparing Your Travel Options
The cheapest way to get from Syracuse to Milan is to bus and fly and train which costs €23 - €190 and takes 5h 2m.
The fastest way to get from Syracuse to Milan is to bus and fly which takes 4h 13m and costs €45 - €200.
No, there is no direct bus from Syracuse to Milan. However, there are services departing from Siracusa - Von Platen and arriving at Milano - Famagosta via Catania Central Bus Station. The journey, including transfers, takes approximately 20h 3m.
Yes, there is an overnight train departing from Siracusa and arriving at Milano Centrale. This train operates every day. The journey takes approximately 20h 35m.
The distance between Syracuse and Milan is 1079 km.
The best way to get from Syracuse to Milan without a car is to train and ferry which takes 13h 15m and costs .
It takes approximately 4h 13m to get from Syracuse to Milan, including transfers.
Syracuse to Milan bus services, operated by Interbus, depart from Siracusa - Von Platen station.
Syracuse to Milan train services, operated by Trenitalia Intercity Night, depart from Siracusa station.
Syracuse to Milan bus services, operated by Interbus, arrive at Catania Via Archimede station.
What companies run services between Syracuse, Italy and Milan, Italy?
You can take a bus from Siracusa - Von Platen to Milano - Famagosta via Catania Via Archimede and Catania Central Bus Station in around 20h 3m. Alternatively, Trenitalia Intercity Night operates a vehicle from Siracusa to Milano Centrale twice daily. Tickets cost €120–210 and the journey takes 20h 35m.
- Website
- ryanair.com
Flights from Catania–Fontanarossa Airport to Milano Malpensa Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €50–170
Flights from Catania–Fontanarossa Airport to Il Caravaggio International Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- €45–220
Flights from Catania–Fontanarossa Airport to Il Caravaggio International Airport via Pescara
- Ave. Duration
- 3h 30m
- When
- Thursday
- Estimated price
- €45–220
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €35–220
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Bari
- Ave. Duration
- 3h 45m
- When
- Wednesday
- Estimated price
- €35–220
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Malta
- Ave. Duration
- 4h 15m
- When
- Monday
- Estimated price
- €35–220
Flights from Catania–Fontanarossa Airport to Verona Villafranca Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €55–270
Flights from Catania–Fontanarossa Airport to Verona Villafranca Airport via Cagliari
- Ave. Duration
- 3h 35m
- When
- Monday, Wednesday, and Saturday
- Estimated price
- €55–270
Flights from Catania–Fontanarossa Airport to Turin Caselle Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €30–240
Flights from Catania–Fontanarossa Airport to Turin Caselle Airport via Cagliari
- Ave. Duration
- 3h 35m
- When
- Saturday
- Estimated price
- €30–240
Flights from Catania–Fontanarossa Airport to Turin Caselle Airport via Naples
- Ave. Duration
- 4h 15m
- When
- Saturday and Monday
- Estimated price
- €30–240
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Siracusa to Messina Centrale
- Ave. Duration
- 2h 53m
- Frequency
- Hourly
- Estimated price
- €20–29
- Website
- Trenitalia
Train from Siracusa to Comiso
- Ave. Duration
- 2h 42m
- Frequency
- 3 times a day
- Estimated price
- €16–23
- Website
- Trenitalia
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Via Archimede
- Ave. Duration
- 1h 19m
- Frequency
- Hourly
- Estimated price
- €3–9
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
Want to know more about travelling around Italy
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Booking & Getting There
Syracuse to Milan train services, operated by Trenitalia Intercity Night, arrive at Milano Centrale station.
Book your Syracuse to Milan bus tickets online with Omio.
There are 13944+ hotels available in Milan.





