There are 8 ways to get from Syracuse to Siena by bus, plane, train, ferry, night train, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, fly to Florence Peretola Airport, train
best- Take the bus from Siracusa - Von Platen to Catania Airportbus
- Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)plane CTA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
6h 2m€39–206Bus, train, ferry
- Take the bus from Siracusa - Von Platen to Catania Via Archimedebus
- Take the train from Catania Centrale to Messina Centraletrain Re
- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Napoli Afragolatrain Fr
- Take the train from Napoli Afragola to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
14h 41mBus
- Take the bus from Siracusa - Von Platen to Catania Airportbus Siracusa
- Take the bus from Catania Airport to Sienabus N597 / ...
15h 54m€53–138Bus, night train, train
- Take the bus from Siracusa - Von Platen to Catania Via Archimedebus
- Take the nighttrain from Catania Centrale to Firenze Campo Martenighttrain Ini
- Take the train from Firenze S.M.N. to Sienatrain Re
19h 48m€100–176Bus, fly to Pisa International Airport, train
- Take the bus from Siracusa - Von Platen to Catania Airportbus
- Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)plane CTA - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
5h 59m€55–234Bus, fly to Bologna Guglielmo Marconi Airport, train
- Take the bus from Siracusa - Von Platen to Catania Airportbus
- Fly from Catania–Fontanarossa Airport (CTA) to Bologna Guglielmo Marconi Airport (BLQ)plane CTA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
6h 42m€41–226Bus via Florence
- Take the bus from Siracusa - Von Platen to Catania Airportbus
- Take the bus from Catania Fontanarossa Airport Bus Stop to Florence Villa Constanza Bus Stationbus
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
19h 31m€65–116Drive, car ferry
- Drive from Syracuse to Tresmestiericar
- Take the carferry from Tresmestieri to Villa S. Giovannicarferry
- Drive from Villa S. Giovanni to Sienacar
10h 32m€183–280
Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR) flights
Comparing Your Travel Options
The cheapest way to get from Syracuse to Siena is to bus via Florence which costs €60 - €120 and takes 19h 31m.
The fastest way to get from Syracuse to Siena is to bus and fly and train which takes 5h 59m and costs €50 - €240.
No, there is no direct bus from Syracuse to Siena. However, there are services departing from Siracusa - Von Platen and arriving at Siena via Catania Airport. The journey, including transfers, takes approximately 15h 54m.
The distance between Syracuse and Siena is 936 km.
The best way to get from Syracuse to Siena without a car is to bus and train and ferry which takes 14h 41m and costs .
It takes approximately 6h 2m to get from Syracuse to Siena, including transfers.
Syracuse to Siena bus services, operated by Interbus, depart from Siracusa - Von Platen station.
Syracuse to Siena bus services, operated by Interbus, arrive at Catania Airport station.
Book your Syracuse to Siena bus tickets online with Omio.
There are 2407+ hotels available in Siena.
What companies run services between Syracuse, Italy and Siena, Italy?
You can take a bus from Siracusa - Von Platen to Siena via Catania Airport in around 15h 54m.
- Website
- ryanair.com
Flights from Catania–Fontanarossa Airport to Pisa International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €35–190
Flights from Catania–Fontanarossa Airport to Pisa International Airport via Malta
- Ave. Duration
- 3h 50m
- When
- Tuesday
- Estimated price
- €35–190
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- €30–200
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Malta
- Ave. Duration
- 3h 50m
- When
- Tuesday
- Estimated price
- €30–200
- Website
- ita-airways.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- €90–180
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Rome
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- €85–200
- Website
- volotea.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €16–110
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- €90–180
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Rome
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- €85–200
- Website
- vueling.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 38m
- When
- Monday, Wednesday, Friday, Sunday, and Saturday
- Estimated price
- €35–200
- Website
- flyulendo.com
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €15–90
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 4h 5m
- Frequency
- Hourly
- Estimated price
- €55–100
- Website
- Trenitalia Frecce
Train from Napoli Afragola to Firenze S.M.N.
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- €65–110
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 5h 38m
- Frequency
- Once daily
- Estimated price
- €50–85
- Website
- Italo Treno
Train from Napoli Afragola to Firenze S.M.N.
- Ave. Duration
- 3h 17m
- Frequency
- 3 times a day
- Estimated price
- €55–90
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 38 min
- Frequency
- 5 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 4h 57m
- Frequency
- 6 times a week
- Estimated price
- €45–85
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
- Phone
- 06 3000
- Website
- Trenitalia ICN
Night train from Catania Centrale to Firenze Campo Marte
- Ave. Duration
- 15h 19m
- Frequency
- Twice daily
- Estimated price
- €85–150
- Website
- Trenitalia ICN
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Via Archimede
- Ave. Duration
- 1h 19m
- Frequency
- Hourly
- Estimated price
- €3–9
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Via Archimede
- Ave. Duration
- 1h 19m
- Frequency
- Hourly
- Estimated price
- €3–9
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Catania Airport to Siena
- Ave. Duration
- 13h 45m
- Frequency
- Twice daily
- Estimated price
- €85–130
- Website
- Flixbus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Catania Airport to Siena
- Ave. Duration
- 14h 55m
- Frequency
- Once daily
- Estimated price
- €50–95
- Website
- Itabus S.p.A.
Bus from Catania Fontanarossa Airport Bus Stop to Florence Villa Constanza Bus Station
- Ave. Duration
- 15h 20m
- Frequency
- Twice daily
- Estimated price
- €55–100
- Website
- Itabus S.p.A.
- Phone
- +39 800 142 424
- [email protected]
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €5–6
- Schedules at
- at-bus.it
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
- Phone
- 090774409
- [email protected]
- Website
- bluferries.it
Car ferry from Tresmestieri to Villa S. Giovanni
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- €19–35
- Schedules at
- bluferries.it
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