There are 9 ways to get from Syracuse to Siena by bus, plane, train, train (Trenitalia), night train, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, fly to Florence Peretola Airport, train
best- Take the bus from Siracusa - Von Platen to Catania Airportbus
- Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)plane CTA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
6h 7m€39–206Train (Trenitalia)
- Take the train from Siracusa to Roma Terminitrain Ic
- Take the train from Roma Termini to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
14h 33m€127–240Bus
- Take the bus from Siracusa - Von Platen to Catania Airportbus Siracusa
- Take the bus from Catania Airport to Sienabus N597 / ...
15h 54m€53–138Night train, train
- Take the nighttrain from Siracusa to Firenze Campo Martenighttrain Ini
- Take the train from Firenze S.M.N. to Sienatrain Re
18h 11m€108–177Bus, fly to Pisa International Airport, train
- Take the bus from Siracusa - Von Platen to Catania Airportbus
- Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)plane CTA - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
6h 4m€55–234Bus, fly to Bologna Guglielmo Marconi Airport, train
- Take the bus from Siracusa - Von Platen to Catania Airportbus
- Fly from Catania–Fontanarossa Airport (CTA) to Bologna Guglielmo Marconi Airport (BLQ)plane CTA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
6h 50m€41–226Bus, fly to Fiumicino International Airport, train
- Take the bus from Siracusa - Von Platen to Catania Airportbus
- Fly from Catania–Fontanarossa Airport (CTA) to Fiumicino International Airport (FCO)plane CTA - FCO
- Take the train from Roma Termini to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
7h 49m€68–205Bus via Florence
- Take the bus from Siracusa - Von Platen to Catania Airportbus
- Take the bus from Catania Fontanarossa Airport Bus Stop to Florence Villa Constanza Bus Stationbus
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
19h 31m€65–116Drive, car ferry
- Drive from Syracuse to Tresmestiericar
- Take the carferry from Tresmestieri to Villa S. Giovannicarferry
- Drive from Villa S. Giovanni to Sienacar
10h 32m€184–280
Syracuse to Siena by train (Trenitalia)
Comparing Your Travel Options
The cheapest way to get from Syracuse to Siena is to bus via Florence which costs €60 - €120 and takes 19h 31m.
The fastest way to get from Syracuse to Siena is to bus and fly and train which takes 6h 4m and costs €50 - €240.
No, there is no direct bus from Syracuse to Siena. However, there are services departing from Siracusa - Von Platen and arriving at Siena via Catania Airport. The journey, including transfers, takes approximately 15h 54m.
No, there is no direct train from Syracuse to Siena. However, there are services departing from Siracusa and arriving at Siena via Roma Termini and Firenze S.M.N.. The journey, including transfers, takes approximately 14h 33m.
The distance between Syracuse and Siena is 936 km.
The best way to get from Syracuse to Siena without a car is to train which takes 14h 33m and costs €120 - €240.
It takes approximately 6h 7m to get from Syracuse to Siena, including transfers.
Syracuse to Siena bus services, operated by Interbus, depart from Siracusa - Von Platen station.
Syracuse to Siena train services, operated by Trenitalia Intercity, depart from Siracusa station.
The best way to get from Syracuse to Siena is to train which takes 14h 33m and costs €120 - €240. Alternatively, you can bus, which costs €50 - €140 and takes 15h 54m.
What companies run services between Syracuse, Italy and Siena, Italy?
You can take a train from Siracusa to Siena via Roma Termini and Firenze S.M.N. in around 14h 33m. Alternatively, you can take a bus from Siracusa - Von Platen to Siena via Catania Airport in around 15h 54m.
- Website
- ryanair.com
Flights from Catania–Fontanarossa Airport to Pisa International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €30–180
Flights from Catania–Fontanarossa Airport to Pisa International Airport via Bari
- Ave. Duration
- 3h 25m
- When
- Tuesday
- Estimated price
- €30–180
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €30–210
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Cagliari
- Ave. Duration
- 3h 35m
- When
- Friday
- Estimated price
- €30–210
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Bari
- Ave. Duration
- 3h 45m
- When
- Wednesday
- Estimated price
- €30–210
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Malta
- Ave. Duration
- 4h 15m
- When
- Monday
- Estimated price
- €30–210
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €22–75
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport via Bari
- Ave. Duration
- 2h 45m
- When
- Saturday
- Estimated price
- €22–75
- Website
- ita-airways.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 3h 38m
- When
- Every day
- Estimated price
- €85–180
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Fiumicino International Airport
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- €85–200
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- €45–120
- Website
- volotea.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €16–110
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- €85–180
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Fiumicino International Airport
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- €85–200
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- €45–120
- Website
- aeroitalia.com
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €21–110
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport via Cagliari
- Ave. Duration
- 3h 40m
- When
- Thursday and Sunday
- Estimated price
- €21–110
- Website
- flyulendo.com
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €15–90
Flights from Catania–Fontanarossa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €22–110
- Website
- vueling.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €35–200
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 40m
- Frequency
- Every 3 hours
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 40m
- Frequency
- Every 3 hours
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Siracusa to Roma Termini
- Ave. Duration
- 10h 51m
- Frequency
- Once daily
- Estimated price
- €85–160
- Website
- Trenitalia Intercity
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- €28–55
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- €28–55
- Website
- Trenitalia Intercity
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 37m
- Frequency
- Every 30 minutes
- Estimated price
- €35–65
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 37m
- Frequency
- Every 30 minutes
- Estimated price
- €35–65
- Website
- Trenitalia Frecce
- Phone
- 06 3000
- Website
- Trenitalia ICN
Night train from Siracusa to Firenze Campo Marte
- Ave. Duration
- 16h 1m
- Frequency
- 5 times a week
- Estimated price
- €95–160
- Website
- Trenitalia ICN
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- 5 times a day
- Estimated price
- €10–18
- Website
- Italo Treno
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Siracusa - Von Platen to Catania Airport
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Catania Airport to Siena
- Ave. Duration
- 13h 45m
- Frequency
- Twice daily
- Estimated price
- €80–130
- Website
- Flixbus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Catania Airport to Siena
- Ave. Duration
- 14h 55m
- Frequency
- Once daily
- Estimated price
- €50–95
- Website
- Itabus S.p.A.
Bus from Catania Fontanarossa Airport Bus Stop to Florence Villa Constanza Bus Station
- Ave. Duration
- 15h 20m
- Frequency
- Twice daily
- Estimated price
- €55–100
- Website
- Itabus S.p.A.
- Phone
- +39 800 142 424
- [email protected]
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €5–6
- Schedules at
- at-bus.it
- Phone
- 090774409
- [email protected]
- Website
- bluferries.it
Car ferry from Tresmestieri to Villa S. Giovanni
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- €19–35
- Schedules at
- bluferries.it
Want to know more about travelling around Italy
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Booking & Getting There
Syracuse to Siena bus services, operated by Interbus, arrive at Catania Airport station.
Syracuse to Siena train services, operated by Trenitalia Intercity, arrive at Roma Termini station.
Book your Syracuse to Siena train tickets online with Omio.
Book your Syracuse to Siena bus tickets online with Omio.
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