There are 4 ways to get from Syracuse to Cleveland Clinic by train (Amtrak), bus (Greyhound), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Syracuse Regional Transportation Center to Cleveland Amtraktrain Lake Shore Limited
6h 49m$104–216Drive 329.2 mi
cheapest- Drive from Syracuse to Cleveland Cliniccar 329.2 mi
5h 53m$61–87Bus (Greyhound)
- Take the bus from Syracuse Bus Station to Cleveland Bus Stationbus Greyhound US0171
9h 1m$63–110Fly
- Fly from Syracuse Hancock International Airport (SYR) to Cleveland-Hopkins International Airport (CLE)plane SYR - CLE
6h 25m$114–711
Syracuse to Cleveland Clinic by bus, foot, and subway (Greyhound)
Questions & Answers
The cheapest way to get from Syracuse to Cleveland Clinic is to bus which costs $60 - $110 and takes 9h 1m.
The fastest way to get from Syracuse to Cleveland Clinic is to drive which takes 5h 53m and costs $60 - $90.
No, there is no direct bus from Syracuse station to Cleveland Clinic. However, there are services departing from Syracuse Bus Station and arriving at Cedar Av & E 93Rd St via West Park Station Stop #4 and West Roadway & Superior Av. The journey, including transfers, takes approximately 9h 1m.
No, there is no direct train from Syracuse to Cleveland Clinic station. However, there are services departing from Syracuse Regional Transportation Center and arriving at E 105Th St-Quincy Av Station via Tower City Station Track 13. The journey, including transfers, takes approximately 6h 49m.
The distance between Syracuse and Cleveland Clinic is 336 miles. The road distance is 331.1 miles.
The best way to get from Syracuse to Cleveland Clinic without a car is to train which takes 6h 49m and costs $100 - $220.
It takes approximately 6h 49m to get from Syracuse to Cleveland Clinic, including transfers.
Syracuse to Cleveland Clinic bus services, operated by Greyhound USA, depart from Syracuse Bus Station.
Syracuse to Cleveland Clinic train services, operated by Amtrak, depart from Syracuse Regional Transportation Center station.
The best way to get from Syracuse to Cleveland Clinic is to train which takes 6h 49m and costs $100 - $220. Alternatively, you can bus, which costs $60 - $110 and takes 9h 1m, you could also fly, which costs $110 - $750 and takes 6h 25m.
What companies run services between Syracuse, NY, USA and Cleveland Clinic, OH, USA?
Amtrak operates a train from Syracuse Regional Transportation Center to Cleveland Amtrak twice daily. Tickets cost $100–220 and the journey takes 5h 48m. Alternatively, Greyhound USA operates a bus from Syracuse Bus Station to Cleveland Bus Station once daily. Tickets cost $50–110 and the journey takes 6h 45m.
- Website
- delta.com
Flights from Syracuse Hancock International Airport to Cleveland-Hopkins International Airport via Detroit
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $110–700
Flights from Syracuse Hancock International Airport to Cleveland-Hopkins International Airport via New York La Guardia
- Ave. Duration
- 5h 51m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–750
Flights from Syracuse Hancock International Airport to Cleveland-Hopkins International Airport via New York JFK
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $130–750
- Website
- aa.com
Flights from Syracuse Hancock International Airport to Cleveland-Hopkins International Airport via Philadelphia
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $130–750
Flights from Syracuse Hancock International Airport to Cleveland-Hopkins International Airport via Reagan Washington
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- $130–750
- Website
- united.com
Flights from Syracuse Hancock International Airport to Cleveland-Hopkins International Airport via Washington Dulles
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $130–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Cleveland Amtrak
- Ave. Duration
- 5h 48m
- Frequency
- Twice daily
- Estimated price
- $100–220
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Syracuse Bus Station to Cleveland Bus Station
- Ave. Duration
- 6h 45m
- Frequency
- Once daily
- Estimated price
- $50–110
- Website
- Greyhound
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More Questions & Answers
Syracuse to Cleveland Clinic bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Syracuse to Cleveland Clinic train services, operated by Amtrak, arrive at Cleveland Amtrak station.
Yes, the driving distance between Syracuse to Cleveland Clinic is 331 miles. It takes approximately 5h 53m to drive from Syracuse to Cleveland Clinic.
There are 534+ hotels available in Cleveland Clinic.