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How to get fromSyracuse to Columbus, OHby bus (Greyhound), train, bus, car, plane, or bus (Flixbus)

Find Transport to Columbus, OH

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There are 8 ways to get from Syracuse to Columbus, OH by bus (Greyhound), train, bus, car, plane, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Syracuse Bus Station to Cleveland Bus Stationbus bus Greyhound US0171
    2. Take the bus from Cleveland Bus Station to Columbusbus bus Greyhound US0105
    10h 20m
    $72–141

  2. Bus via Buffalo

    cheapest
    1. Take the bus from Syracuse Bus Station to Buffalo Niagara International Airportbus bus FlixBus 2686 / ...
    2. Take the bus from Buffalo, NY to Columbus - Mound Stbus bus Buffalo
    11h 51m
    $64–198

  3. Train, bus via Brook Park

    1. Take the train from Syracuse Regional Transportation Center to Cleveland Amtraktrain train Lake Shore Limited
    2. Take the bus from Cleveland Bus Station to Columbusbus bus Greyhound US0105
    10h 26m
    $121–252

  4. Drive 470.4 mi

    1. Drive from Syracuse to Columbus, OHcar car 470.4 mi
    8h 2m
    $86–124

  5. Fly from Syracuse Hancock International Airport

    1. Fly from Syracuse Hancock International Airport (SYR) to John Glenn Columbus International Airport (CMH)plane plane SYR - CMH
    6h 41m
    $502–1,238

  6. Train, bus

    1. Take the train from Syracuse Regional Transportation Center to Cleveland Amtraktrain train Lake Shore Limited
    2. Take the bus from Cleveland Ohio Greyhound Station to Columbus, Ohio Greyhound Stationbus bus 379 D
    12h 32m
    $160–433

  7. Train to Rochester, fly

    1. Take the train from Syracuse Regional Transportation Center to Rochestertrain train
    2. Fly from Rochester (ROC) to John Glenn Columbus International Airport (CMH)plane plane ROC - CMH
    7h 10m
    $542–1,313

  8. Bus to Greater Binghamton Airport, fly

    1. Take the bus from Syracuse to Binghamtonbus bus
    2. Fly from Greater Binghamton Airport (BGM) to John Glenn Columbus International Airport (CMH)plane plane BGM - CMH
    7h 57m
    $137–647

Syracuse to Columbus, OH by bus and foot (Greyhound)

Calendar7Weekly Services
Duration10h 20mAverage Duration
Ticket$72Cheapest Price
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Questions & Answers

Map of how to get from Syracuse to Columbus, OH.ExpandLaunch map view
  • Distance: 491.9 mi
  • Duration: 10h 20m

What companies run services between Syracuse, NY, USA and Columbus, OH, USA?

You can take a bus from Syracuse Bus Station to Columbus, OH via Cleveland Bus Station and Columbus in around 10h 20m. Alternatively, United Airlines, Delta, and American Airlines fly from Syracuse Hancock International Airport (SYR) to John Glenn Columbus International Airport (CMH) hourly.

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