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How to get fromSyracuse to Detroitby plane, train, bus, bus (Greyhound), car, or bus (Flixbus)

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There are 9 ways to get from Syracuse to Detroit by plane, train, bus, bus (Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Syracuse Hancock International Airport

    best
    1. Fly from Syracuse Hancock International Airport (SYR) to Detroit (DTW)plane plane SYR - DTW
    4h 31m
    $98–610

  2. Drive 398.7 mi

    cheapest
    1. Drive from Syracuse to Detroitcar car 398.7 mi
    7h 10m
    $73–106

  3. Train, bus

    1. Take the train from Syracuse Regional Transportation Center to Toledotrain train Lake Shore Limited
    2. Take the bus from Toledo Bus Stop to Detroit Bus Stationbus bus Greyhound US0135 / ...
    10h 1m
    $143–325

  4. Bus (Greyhound)

    1. Take the bus from Syracuse Bus Station to Cleveland Bus Stationbus bus Greyhound US0171
    2. Take the bus from Cleveland Bus Station to Detroit Bus Stationbus bus Greyhound US0420
    11h 5m
    $78–152

  5. Train to Rochester, fly

    1. Take the train from Syracuse Regional Transportation Center to Rochestertrain train
    2. Fly from Rochester (ROC) to Detroit (DTW)plane plane ROC - DTW
    5h 7m
    $123–736

  6. Bus to Buffalo Niagara International Airport, fly

    1. Take the bus from Syracuse Bus Station to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Detroit (DTW)plane plane BUF - DTW
    6h 21m
    $104–641

  7. Bus to Greater Binghamton Airport, fly

    1. Take the bus from Syracuse to Binghamtonbus bus
    2. Fly from Greater Binghamton Airport (BGM) to Detroit (DTW)plane plane BGM - DTW
    5h 22m
    $113–479

  8. Train

    1. Take the train from Syracuse to Aldershottrain train VIA Rail
    2. Take the train from Aldershot to Windsortrain train VIA Rail
    10h 40m
    $110–410

  9. Bus via Toronto

    1. Take the bus from Syracuse to Torontobus bus Adt N816
    2. Take the bus from Toronto to Detroit Bus Stationbus bus FlixBus 2701 / ...
    14h 5m
    $76–224

Syracuse to Detroit by train and bus

Calendar14Weekly Services
Duration10h 1mAverage Duration
Ticket$143Cheapest Price
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Questions & Answers

Map of how to get from Syracuse to Detroit.ExpandLaunch map view
  • Distance: 409.9 mi
  • Duration: 4h 31m

What companies run services between Syracuse, NY, USA and Detroit, MI, USA?

Delta and United Airlines fly from Syracuse Hancock International Airport (SYR) to Detroit (DTW) every 4 hours. Alternatively, you can take a bus from Syracuse Bus Station to Detroit Bus Station via Cleveland Bus Station in around 11h 5m.

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