There are 9 ways to get from Syracuse to Duke University by plane, bus, train, car, bus (Greyhound), or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Syracuse Hancock International Airport to Raleigh-Durham International Airport, bus, line 700 bus, line 6 bus
best- Fly from Syracuse Hancock International Airport (SYR) to Raleigh-Durham International Airport (RDU)plane SYR - RDU
- Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
- Take the bus from Regional Transit Center to Duke St at Jackson Stbus
- Take the bus from Jackson St at Duke St to Flowers Dr at Duke Gardensbus
5h 23m$108–615Bus to Ithaca Tompkins Regional Airport, fly to Raleigh-Durham International Airport
cheapest- Take the bus from Syracuse Bus Station to Ithacabus
- Fly from Ithaca Tompkins Regional Airport (ITH) to Raleigh-Durham International Airport (RDU)plane ITH - RDU
8h 59m$82–413Bus via New York
- Take the bus from Syracuse to New Yorkbus Adt N801 / ...
- Take the bus from New York, NY to Durhambus Nyc
13h 41m$120–270Bus, train
- Take the bus from Syracuse Bus Station to Newark Penn Stationbus FlixBus N2685 / ...
- Take the train from Newark Penn Station to Durham Amtrak Stationtrain Carolinian
18h 33m$210–432Drive 619.6 mi
- Drive from Syracuse to Duke Universitycar 619.6 mi
11h 11m$114–164Train to Rochester, fly to Raleigh-Durham International Airport
- Take the train from Syracuse Regional Transportation Center to Rochestertrain
- Fly from Rochester (ROC) to Raleigh-Durham International Airport (RDU)plane ROC - RDU
6h 15m$168–1,091Fly Syracuse Hancock International Airport to Piedmont Triad International Airport, train
- Fly from Syracuse Hancock International Airport (SYR) to Piedmont Triad International Airport (GSO)plane SYR - GSO
- Take the train from Greensboro to Durham Amtrak Stationtrain
8h 7m$188–884Bus
- Take the bus from Syracuse Bus Station to Port Authority Bus Terminalbus Greyhound US0205 / ...
- Take the bus from New York, NY - 201 West x 37th St to Durham, NC - 3446 Hillsborough Rdbus New York
15h 37m$86–231Train (Amtrak)
- Take the train from Syracuse Regional Transportation Center to Ny Moynihan Train Hall At Penn Stationtrain Empire Service / ...
- Take the train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Stationtrain Carolinian
20h 6m$264–562
Syracuse to Duke University by bus, train, and foot
Questions & Answers
The cheapest way to get from Syracuse to Duke University is to drive which costs $110 - $170 and takes 11h 11m.
The fastest way to get from Syracuse to Duke University is to fly and bus and line 700 bus and line 6 bus which takes 5h 23m and costs $100 - $650.
No, there is no direct bus from Syracuse to Duke University. However, there are services departing from Syracuse and arriving at Flowers Dr at Duke Gardens via New York, NY, North Pointe Dr at Woodmont Dr and Jackson St at Duke St. The journey, including transfers, takes approximately 13h 41m.
No, there is no direct train from Syracuse to Duke University station. However, there are services departing from Syracuse Regional Transportation Center and arriving at Durham Amtrak Station via Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 20h 6m.
The distance between Syracuse and Duke University is 556 miles. The road distance is 623.2 miles.
The best way to get from Syracuse to Duke University without a car is to bus via New York which takes 13h 41m and costs $120 - $270.
It takes approximately 5h 23m to get from Syracuse to Duke University, including transfers.
Syracuse to Duke University bus services, operated by Trailways, depart from Syracuse station.
Syracuse to Duke University train services, operated by Amtrak, depart from Syracuse Regional Transportation Center station.
The best way to get from Syracuse to Duke University is to bus via New York which takes 13h 41m and costs $120 - $270. Alternatively, you can train, which costs $260 - $600 and takes 20h 6m.
What companies run services between Syracuse, NY, USA and Duke University, NC, USA?
You can take a bus from Syracuse to Duke University via New York, 42 St-Times Square, Canal St, New York, NY, Durham, North Pointe Dr at Woodmont Dr, Chapel Hill St at Duke St, Jackson St at Duke St, and Flowers Dr at Duke Gardens in around 13h 41m. Alternatively, you can take a train from Syracuse Regional Transportation Center to Duke University via Ny Moynihan Train Hall At Penn Station, Durham Amtrak Station, Durham Station, and Flowers Dr at Duke Gardens in around 20h 6m.
- Website
- aa.com
Flights from Syracuse Hancock International Airport to Raleigh-Durham International Airport via Reagan Washington
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $100–600
Flights from Syracuse Hancock International Airport to Raleigh-Durham International Airport via Philadelphia
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $100–600
Flights from Syracuse Hancock International Airport to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $120–650
Flights from Rochester to Raleigh-Durham International Airport via Philadelphia
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $100–600
Flights from Rochester to Raleigh-Durham International Airport via Reagan Washington
- Ave. Duration
- 3h 54m
- When
- Sunday
- Estimated price
- $95–550
Flights from Rochester to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 4h
- When
- Sunday
- Estimated price
- $110–600
Flights from Syracuse Hancock International Airport to Piedmont Triad International Airport via Charlotte
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $160–900
Flights from Syracuse Hancock International Airport to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 5h 4m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–800
Flights from Syracuse Hancock International Airport to Piedmont Triad International Airport via Philadelphia
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- $150–850
Flights from Syracuse Hancock International Airport to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 6h 42m
- When
- Every day
- Estimated price
- $240–1,100
- Website
- united.com
Flights from Syracuse Hancock International Airport to Raleigh-Durham International Airport via Washington Dulles
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $100–600
Flights from Rochester to Raleigh-Durham International Airport via Washington Dulles
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $95–550
Flights from Syracuse Hancock International Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- $140–800
Flights from Ithaca Tompkins Regional Airport to Raleigh-Durham International Airport via Washington Dulles
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- $65–390
- Website
- delta.com
Flights from Syracuse Hancock International Airport to Raleigh-Durham International Airport via New York La Guardia
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $110–600
Flights from Rochester to Raleigh-Durham International Airport via Detroit
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $120–650
Flights from Syracuse Hancock International Airport to Piedmont Triad International Airport via Detroit
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $190–950
Flights from Syracuse Hancock International Airport to Piedmont Triad International Airport via New York La Guardia
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $160–850
Flights from Syracuse Hancock International Airport to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 5h 1m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $230–1,100
Flights from Ithaca Tompkins Regional Airport to Raleigh-Durham International Airport via New York JFK
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $80–430
- Website
- southwest.com
Flights from Rochester to Raleigh-Durham International Airport via Baltimore
- Ave. Duration
- 3h 28m
- When
- Sunday, Monday, Thursday, Friday, Tuesday, and Wednesday
- Estimated price
- $95–550
- Website
- flybreeze.com
Flights from Syracuse Hancock International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 44m
- When
- Monday, Friday, and Wednesday
- Estimated price
- $220–1,500
Flights from Rochester to Raleigh-Durham International Airport
- Ave. Duration
- 1h 45m
- When
- Monday, Friday, Wednesday, and Saturday
- Estimated price
- $120–900
- Website
- jetblue.com
Flights from Syracuse Hancock International Airport to Raleigh-Durham International Airport via New York JFK
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $110–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Newark Penn Station to Durham Amtrak Station
- Ave. Duration
- 12h 31m
- Frequency
- Once daily
- Estimated price
- $170–360
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Rochester
- Ave. Duration
- 1h 16m
- Frequency
- 5 times a day
- Estimated price
- $25–55
- Website
- Amtrak
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $17–40
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 5h 39m
- Frequency
- 4 times a day
- Estimated price
- $90–200
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Station
- Ave. Duration
- 12h 51m
- Frequency
- Once daily
- Estimated price
- $170–370
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Syracuse Regional Transportation Center to Rochester
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- $21–170
- Website
- VIA Rail
- Escape
- $21–75
- Business
- $50–150
- Business Plus
- $65–170
- Economy
- $24–80
- Economy Plus
- $26–90
- Phone
- +1 919 485 7433
- [email protected]
- Website
- gotriangle.org
Bus from RDU Airport at Terminal 2 to Regional Transit Center
- Ave. Duration
- 12 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- gotriangle.org
- Regular one-way fare
- $3
Bus from Regional Transit Center to Duke St at Jackson St
- Ave. Duration
- 33 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- gotriangle.org
- Phone
- +1 919-485-7433
- Website
- godurhamtransit.org
Bus from Jackson St at Duke St to Flowers Dr at Duke Gardens
- Ave. Duration
- 11 min
- Frequency
- Hourly
- Estimated price
- $1
- Schedules at
- godurhamtransit.org
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Syracuse to New York
- Ave. Duration
- 4h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–160
- Website
- Trailways
- Schedules at
- Trailways
- Saver
- $40–150
- Flexible
- $70–160
Bus from Syracuse Bus Station to Port Authority Bus Terminal
- Ave. Duration
- 4h 50m
- Frequency
- 4 times a day
- Estimated price
- $40–160
- Website
- Trailways
- Schedules at
- Trailways
- Saver
- $40–150
- Flexible
- $70–160
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from New York, NY to Durham
- Ave. Duration
- 6h 24m
- Frequency
- 4 times a day
- Estimated price
- $75–110
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $75–110
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Syracuse Bus Station to Newark Penn Station
- Ave. Duration
- 4h 30m
- Frequency
- Every 2 hours
- Estimated price
- $35–65
- Schedules at
- Flixbus USA
Bus from Syracuse Bus Station to Ithaca
- Ave. Duration
- 1h 9m
- Frequency
- 6 times a week
- Estimated price
- $9–17
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Syracuse Bus Station to Newark Penn Station
- Ave. Duration
- 4h 35m
- Frequency
- Twice daily
- Estimated price
- $35–70
- Website
- Greyhound
Bus from Syracuse Bus Station to Port Authority Bus Terminal
- Ave. Duration
- 4h 45m
- Frequency
- Every 2 hours
- Estimated price
- $35–75
- Website
- Greyhound
- Phone
- +1 617-681-0820
- [email protected]
- Website
- CoachRun
Bus from New York, NY - 201 West x 37th St to Durham, NC - 3446 Hillsborough Rd
- Ave. Duration
- 9h
- Frequency
- 5 times a week
- Estimated price
- $45–75
- Website
- CoachRun
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Syracuse to Duke University bus services, operated by Trailways, arrive at New York station.
Syracuse to Duke University train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Syracuse to Duke University is 623 miles. It takes approximately 11h 11m to drive from Syracuse to Duke University.
There are 408+ hotels available in Duke University.


















