Rome2Rio

How to get fromSyracuse to Florida Keysby plane, bus, train, bus (Flixbus, Greyhound), car, shuttle, or ferry

Find Transport to Florida Keys

See all options

There are 9 ways to get from Syracuse to Florida Keys by plane, bus, train, bus (Flixbus, Greyhound), car, shuttle, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Syracuse Hancock International Airport to Key West International Airport

    best
    1. Fly from Syracuse Hancock International Airport (SYR) to Key West International Airport (EYW)plane plane SYR - EYW
    10h 42m
    $208–702

  2. Bus, train

    1. Take the bus from Syracuse Bus Station to Newark Penn Stationbus bus
    2. Take the train from Newark Penn Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    39h 54m
    $507–1,087

  3. Bus

    1. Take the bus from Syracuse Bus Station to Ithacabus bus
    2. Take the bus from Ithaca to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Miamibus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    41h 28m
    $293–505

  4. Drive 1,552.3 mi

    1. Drive from Syracuse to Florida Keyscar car 1,552.3 mi
    27h 2m
    $284–410

  5. Train to Rochester, fly to Key West International Airport

    1. Take the train from Syracuse Regional Transportation Center to Rochestertrain train
    2. Fly from Rochester (ROC) to Key West International Airport (EYW)plane plane ROC - EYW
    11h 22m
    $238–878

  6. Fly Syracuse Hancock International Airport to Miami International Airport, shuttle

    1. Fly from Syracuse Hancock International Airport (SYR) to Miami International Airport (MIA)plane plane SYR - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 34m
    $303–892

  7. Fly Syracuse Hancock International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Syracuse Hancock International Airport (SYR) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane SYR - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 43m
    $323–912

  8. Bus to Newark Liberty International Airport, fly to Key West International Airport

    1. Take the bus from Syracuse Bus Station to Newark Penn Stationbus bus
    2. Fly from Newark Liberty International Airport (EWR) to Key West International Airport (EYW)plane plane EWR - EYW
    12h 15m
    $222–598

  9. Fly Syracuse Hancock International Airport to Ft. Myers, ferry

    1. Fly from Syracuse Hancock International Airport (SYR) to Ft. Myers (RSW)plane plane SYR - RSW
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    13h 25m
    $327–938

Syracuse to Florida Keys by bus, train, taxi, and foot

Calendar7Weekly Services
Duration39h 54mAverage Duration
Ticket$507Cheapest Price
See schedules

Questions & Answers

Map of how to get from Syracuse to Florida Keys.ExpandLaunch map view
  • Distance: 1,357.2 mi
  • Duration: 10h 42m

What companies run services between Syracuse, NY, USA and Florida Keys, FL, USA?

American Airlines and Delta fly from Syracuse Hancock International Airport (SYR) to Key West International Airport (EYW) twice daily. Alternatively, you can take a bus from Syracuse Bus Station to Florida Keys via Ithaca, Washington Union Station, Miami, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 41h 28m.

Airlines
Train operators
Bus operators
Ferry operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers