There are 5 ways to get from Syracuse to Great Lakes by plane, train (Amtrak), bus (Greyhound), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Syracuse Hancock International Airport
best- Fly from Syracuse Hancock International Airport (SYR) to Chicago O'Hare International Airport (ORD)plane SYR - ORD
4h 35m$83–453Train (Amtrak)
- Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain Lake Shore Limited
13h 19m$209–436Bus (Greyhound)
- Take the bus from Syracuse Bus Station to Cleveland Bus Stationbus Greyhound US0171
- Take the bus from Cleveland Bus Station to Chicago Bus Stationbus Greyhound US0164
15h 29m$107–204Drive 675.5 mi
- Drive from Syracuse to Chicagocar 675.5 mi
11h 31m$124–179Train to Rochester, fly
- Take the train from Syracuse Regional Transportation Center to Rochestertrain
- Fly from Rochester (ROC) to Chicago O'Hare International Airport (ORD)plane ROC - ORD
5h 15m$108–579
Syracuse to Great Lakes by train and bus (Amtrak)
Questions & Answers
The cheapest way to get from Syracuse to Great Lakes is to bus which costs $100 - $210 and takes 15h 29m.
The fastest way to get from Syracuse to Great Lakes is to fly which takes 4h 35m and costs $80 - $460.
No, there is no direct bus from Syracuse station to Great Lakes. However, there are services departing from Syracuse Bus Station and arriving at Jackson & Wabash via Cleveland Bus Station and Jackson & Clinton. The journey, including transfers, takes approximately 15h 29m.
No, there is no direct train from Syracuse to Great Lakes station. However, there are services departing from Syracuse Regional Transportation Center and arriving at Chicago Union Station via . The journey, including transfers, takes approximately 13h 19m.
The distance between Syracuse and Great Lakes is 640 miles. The road distance is 679.5 miles.
The best way to get from Syracuse to Great Lakes without a car is to train which takes 13h 19m and costs $200 - $440.
It takes approximately 4h 35m to get from Syracuse to Great Lakes, including transfers.
Syracuse to Great Lakes bus services, operated by Greyhound USA, depart from Syracuse Bus Station.
Syracuse to Great Lakes train services, operated by Amtrak, depart from Syracuse Regional Transportation Center station.
The best way to get from Syracuse to Great Lakes is to fly which takes 4h 35m and costs $80 - $460. Alternatively, you can train, which costs $200 - $440 and takes 13h 19m, you could also bus, which costs $100 - $210 and takes 15h 29m.
What companies run services between Syracuse, NY, USA and Great Lakes, MI, USA?
American Airlines, United Airlines, and Delta fly from Syracuse Hancock International Airport (SYR) to Chicago O'Hare International Airport (ORD) hourly. Alternatively, Amtrak operates a train from Syracuse Regional Transportation Center to Chicago Union Station twice daily. Tickets cost $200–440 and the journey takes 13h 7m.
- Website
- united.com
Flights from Syracuse Hancock International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 19m
- When
- Every day
- Estimated price
- $80–440
Flights from Syracuse Hancock International Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $100–550
Flights from Rochester to Chicago O'Hare International Airport
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- $65–390
Flights from Rochester to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $90–470
- Website
- aa.com
Flights from Syracuse Hancock International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 27m
- When
- Every day
- Estimated price
- $80–440
Flights from Rochester to Chicago O'Hare International Airport
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $65–390
Flights from Rochester to Chicago O'Hare International Airport via Reagan Washington
- Ave. Duration
- 4h 51m
- When
- Monday to Saturday
- Estimated price
- $95–470
Flights from Rochester to Chicago O'Hare International Airport via Philadelphia
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $95–480
- Website
- delta.com
Flights from Syracuse Hancock International Airport to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $80–440
Flights from Syracuse Hancock International Airport to Chicago O'Hare International Airport via New York La Guardia
- Ave. Duration
- 4h 59m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
Flights from Rochester to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $65–390
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Chicago Union Station
- Ave. Duration
- 13h 7m
- Frequency
- Twice daily
- Estimated price
- $200–440
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Rochester
- Ave. Duration
- 1h 16m
- Frequency
- 5 times a day
- Estimated price
- $24–55
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Syracuse Regional Transportation Center to Rochester
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- $21–170
- Website
- VIA Rail
- Escape
- $21–75
- Business
- $50–150
- Business Plus
- $65–170
- Economy
- $24–80
- Economy Plus
- $26–85
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Syracuse Bus Station to Cleveland Bus Station
- Ave. Duration
- 6h 45m
- Frequency
- Once daily
- Estimated price
- $50–110
- Website
- Greyhound
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Twice daily
- Estimated price
- $50–100
- Website
- Greyhound
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More Questions & Answers
Syracuse to Great Lakes bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Syracuse to Great Lakes train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Syracuse to Great Lakes is 679 miles. It takes approximately 11h 31m to drive from Syracuse to Great Lakes.
There are 58+ hotels available in Great Lakes.










