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How to get fromSyracuse to Hopkintonby bus (Greyhound, Flixbus), train (Amtrak), car, plane, train, or bus (Flixbus)

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There are 6 ways to get from Syracuse to Hopkinton by bus (Greyhound, Flixbus), train (Amtrak), car, plane, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Syracuse Bus Station to Springfield Union Stationbus bus Greyhound US0171 / ...
    2. Take the bus from Springfield Union Station to Framinghambus bus Greyhound US0270s
    8h 22m
    $46–85

  2. Train (Amtrak)

    1. Take the train from Syracuse Regional Transportation Center to Framingham Amtraktrain train Lake Shore Limited
    9h 33m
    $106–217

  3. Drive 286.5 mi

    1. Drive from Syracuse to Hopkintoncar car 286.5 mi
    5h
    $53–76

  4. Fly from Syracuse Hancock International Airport, train

    1. Fly from Syracuse Hancock International Airport (SYR) to Boston Logan Airport (BOS)plane plane SYR - BOS
    2. Take the train from Back Bay to Southboroughtrain train
    6h 6m
    $76–430

  5. Bus via West Albany

    1. Take the bus from Syracuse Bus Station to Albanybus bus FlixBus 2691
    2. Take the bus from Albany Bus Terminal, NY to Worcester Union Stationbus bus FlixBus 2693
    10h 25m
    $50–125

  6. Train to Rochester, fly, train

    1. Take the train from Syracuse Regional Transportation Center to Rochestertrain train
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    3. Take the train from Back Bay to Southboroughtrain train
    7h 16m
    $121–606

Syracuse to Hopkinton by bus

Calendar14Weekly Buses
Duration8h 22mAverage Duration
Ticket$46Cheapest Price
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Questions & Answers

Map of how to get from Syracuse to Hopkinton.ExpandLaunch map view
  • Distance: 297.1 mi
  • Duration: 8h 22m

What companies run services between Syracuse, NY, USA and Hopkinton, MA, USA?

You can take a bus from Syracuse Bus Station to Hopkinton Center via Springfield Union Station, Framingham, and Framingham MBTA Station in around 8h 22m. Alternatively, Amtrak operates a train from Syracuse Regional Transportation Center to Framingham Amtrak once daily. Tickets cost $100–220 and the journey takes 8h 16m.

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