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How to get fromSyracuse to Hyannisby bus (Greyhound, Flixbus), train, bus, car, plane, or bus (Flixbus)

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There are 6 ways to get from Syracuse to Hyannis by bus (Greyhound, Flixbus), train, bus, car, plane, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Syracuse Bus Station to Bostonbus bus Greyhound US0171 / ...
    2. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus Hyannis - South Shore to Logan Airport
    8h 57m
    $74–123

  2. Drive 367.6 mi

    cheapest
    1. Drive from Syracuse to Hyanniscar car 367.6 mi
    6h 34m
    $68–97

  3. Train, bus

    1. Take the train from Syracuse Regional Transportation Center to Bostontrain train Lake Shore Limited
    2. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus Hyannis - South Shore to Logan Airport
    11h 22m
    $138–264

  4. Fly to Barnstable Municipal Airport

    1. Fly from Syracuse Hancock International Airport (SYR) to Barnstable Municipal Airport (HYA)plane plane SYR - HYA
    5h 47m
    $81–558

  5. Bus via West Albany

    1. Take the bus from Syracuse Bus Station to Albanybus bus
    2. Take the bus from Albany to Bostonbus bus
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    9h 57m
    $78–122

  6. Fly to Boston Logan Airport, bus

    1. Fly from Syracuse Hancock International Airport (SYR) to Boston Logan Airport (BOS)plane plane SYR - BOS
    2. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    5h 32m
    $89–448

Syracuse to Hyannis by bus

Calendar34Weekly Buses
Duration8h 57mAverage Duration
Ticket$74Cheapest Price
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Questions & Answers

Map of how to get from Syracuse to Hyannis.ExpandLaunch map view
  • Distance: 383.4 mi
  • Duration: 8h 57m

What companies run services between Syracuse, NY, USA and Hyannis, MA, USA?

You can take a bus from Syracuse Bus Station to Hyannis Transportation Center via Boston and Boston South Buses in around 8h 57m. Alternatively, American Airlines, JetBlue Airways, and two other airlines fly from Syracuse Hancock International Airport (SYR) to Barnstable Municipal Airport (HYA) 3 times a day.

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