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How to get fromSyracuse to Indianaby plane, train, bus, bus (Greyhound), car, or train (Amtrak)

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There are 9 ways to get from Syracuse to Indiana by plane, train, bus, bus (Greyhound), car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Syracuse Hancock International Airport to South Bend

    best
    1. Fly from Syracuse Hancock International Airport (SYR) to South Bend (SBN)plane plane SYR - SBN
    6h 11m
    $146–776

  2. Fly Syracuse Hancock International Airport to Chicago O'Hare International Airport, train

    cheapest
    1. Fly from Syracuse Hancock International Airport (SYR) to Chicago O'Hare International Airport (ORD)plane plane SYR - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    5h 56m
    $85–442

  3. Train, bus

    1. Take the train from Syracuse Regional Transportation Center to Toledotrain train Lake Shore Limited
    2. Take the bus from Toledo to Indianapolis, INbus bus Detroit
    13h 13m
    $159–350

  4. Bus

    1. Take the bus from Syracuse Bus Station to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Toledo Bus Stopbus bus
    3. Take the bus from Toledo to Indianapolis, INbus bus
    14h 35m
    $90–197

  5. Drive 640.2 mi

    1. Drive from Syracuse to Indianapoliscar car 640.2 mi
    11h 3m
    $117–169

  6. Fly Syracuse Hancock International Airport to Fort Wayne International Airport

    1. Fly from Syracuse Hancock International Airport (SYR) to Fort Wayne International Airport (FWA)plane plane SYR - FWA
    5h 30m
    $121–533

  7. Train to Rochester, fly to Chicago Midway International Airport, train

    1. Take the train from Syracuse Regional Transportation Center to Rochestertrain train
    2. Fly from Rochester (ROC) to Chicago Midway International Airport (MDW)plane plane ROC - MDW
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    6h 3m
    $130–648

  8. Train to Rochester, fly to Chicago O'Hare International Airport, train

    1. Take the train from Syracuse Regional Transportation Center to Rochestertrain train
    2. Fly from Rochester (ROC) to Chicago O'Hare International Airport (ORD)plane plane ROC - ORD
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    6h 36m
    $115–578

  9. Train (Amtrak)

    1. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    19h 1m
    $273–568

Syracuse to Indiana by train and bus

Calendar7Weekly Services
Duration13h 13mAverage Duration
Ticket$159Cheapest Price
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Questions & Answers

Map of how to get from Syracuse to Indiana.ExpandLaunch map view
  • Distance: 547.3 mi
  • Duration: 6h 11m

What companies run services between Syracuse, NY, USA and Indiana, USA?

Delta, United Airlines, and American Airlines fly from Syracuse Hancock International Airport (SYR) to South Bend (SBN) every 4 hours. Alternatively, you can take a bus from Syracuse Bus Station to Indianapolis, IN via Cleveland Bus Station and Toledo in around 14h 35m.

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