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How to get fromSyracuse to Iowaby plane, train, bus, bus (Greyhound), or car

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There are 9 ways to get from Syracuse to Iowa by plane, train, bus, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines

    best
    1. Fly from Syracuse Hancock International Airport (SYR) to Des Moines (DSM)plane plane SYR - DSM
    6h 21m
    $218–1,029

  2. Fly to Quad City International Airport

    cheapest
    1. Fly from Syracuse Hancock International Airport (SYR) to Quad City International Airport (MLI)plane plane SYR - MLI
    7h 50m
    $103–560

  3. Train, bus

    1. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    20h 51m
    $271–543

  4. Bus (Greyhound)

    1. Take the bus from Syracuse Bus Station to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    22h 45m
    $162–308

  5. Drive 991.2 mi

    1. Drive from Syracuse to Des Moinescar car 991.2 mi
    16h 45m
    $181–262

  6. Fly to The Eastern Iowa Airport

    1. Fly from Syracuse Hancock International Airport (SYR) to The Eastern Iowa Airport (CID)plane plane SYR - CID
    6h 22m
    $151–658

  7. Fly to Omaha

    1. Fly from Syracuse Hancock International Airport (SYR) to Omaha (OMA)plane plane SYR - OMA
    6h 48m
    $196–838

  8. Fly to Waterloo Municipal Airport

    1. Fly from Syracuse Hancock International Airport (SYR) to Waterloo Municipal Airport (ALO)plane plane SYR - ALO
    6h 52m
    $129–631

  9. Train, bus via Galesburg

    1. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    3. Take the bus from Galesburg to Des Moinesbus bus
    22h 43m
    $301–618

Syracuse Hancock International Airport (SYR) to Des Moines (DSM) flights

Calendar92Weekly Planes
Duration6h 27mAverage Duration
Ticket$206Cheapest Price
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Questions & Answers

Map of how to get from Syracuse to Iowa.ExpandLaunch map view
  • Distance: 921.5 mi
  • Duration: 6h 21m

What companies run services between Syracuse, NY, USA and Iowa, USA?

United Airlines, Delta, and American Airlines fly from Syracuse Hancock International Airport (SYR) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Syracuse Bus Station to Des Moines via Cleveland Bus Station, Chicago Bus Station, and Des Moines in around 22h 45m.

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