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How to get fromSyracuse to Lake Cityby plane, bus, train, bus (Flixbus, Greyhound), car, or bus (Greyhound)

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There are 10 ways to get from Syracuse to Lake City by plane, bus, train, bus (Flixbus, Greyhound), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Jacksonville, bus

    best
    1. Fly from Syracuse Hancock International Airport (SYR) to Jacksonville (JAX)plane plane SYR - JAX
    2. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    9h 38m
    $150–728

  2. Fly to Gainesville Regional Airport, bus

    cheapest
    1. Fly from Syracuse Hancock International Airport (SYR) to Gainesville Regional Airport (GNV)plane plane SYR - GNV
    2. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    11h 52m
    $141–674

  3. Bus, train

    1. Take the bus from Syracuse to Newarkbus bus
    2. Take the train from Newark Penn Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    26h 30m
    $336–812

  4. Bus

    1. Take the bus from Syracuse to New Yorkbus bus
    2. Take the bus from New York City Chinatown to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    26h 55m
    $191–415

  5. Drive 1,118 mi

    1. Drive from Syracuse to Lake Citycar car 1,118 mi
    19h 23m
    $204–295

  6. Fly to Orlando, bus

    1. Fly from Syracuse Hancock International Airport (SYR) to Orlando (MCO)plane plane SYR - MCO
    2. Take the bus from Orlando Bus Station to Lake City Bus Stationbus bus
    10h 46m
    $348–657

  7. Fly to Orlando Sanford, drive

    1. Fly from Syracuse Hancock International Airport (SYR) to Orlando Sanford (SFB)plane plane SYR - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Lake Citycar car
    7h 19m
    $159–753

  8. Fly to Valdosta, bus

    1. Fly from Syracuse Hancock International Airport (SYR) to Valdosta (VLD)plane plane SYR - VLD
    2. Take the bus from Valdosta to Gainesville Bus Stopbus bus
    3. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    12h 6m
    $165–716

  9. Train, bus

    1. Take the train from Syracuse Regional Transportation Center to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    28h 27m
    $387–855

  10. Bus via Camden

    1. Take the bus from Syracuse Bus Station to Port Authority Bus Terminalbus bus
    2. Take the bus from New York, NY to Camdenbus bus Nyc
    3. Take the bus from Camden to Jacksonvillebus bus
    4. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    30h 25m
    $191–405

Syracuse to Lake City by bus and train

Calendar7Weekly Services
Duration26h 30mAverage Duration
Ticket$336Cheapest Price
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Questions & Answers

Map of how to get from Syracuse to Lake City.ExpandLaunch map view
  • Distance: 1,016.6 mi
  • Duration: 9h 38m

What companies run services between Syracuse, NY, USA and Lake City, FL, USA?

You can take a bus from Syracuse to Lake City Bus Station via New York, 42 St-Times Square, Canal St, New York City Chinatown, and Jacksonville in around 26h 55m.

Airlines
Train operators
Bus operators

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