There are 7 ways to get from Syracuse to Lowell by plane, train, bus (Greyhound, Flixbus), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Syracuse Hancock International Airport, train
best- Fly from Syracuse Hancock International Airport (SYR) to Boston Logan Airport (BOS)plane SYR - BOS
- Take the train from Anderson/Woburn to Lowelltrain
4h 37m$72–425Bus
cheapest- Take the bus from Syracuse Bus Station to Bostonbus Greyhound US0171 / ...
- Take the bus from Boston to Robert B Kennedy Bus Transfer Centerbus Greyhound US0256S
8h 10m$51–96Train
- Take the train from Syracuse Regional Transportation Center to Bostontrain Lake Shore Limited
- Take the train from North Station to Lowelltrain Lowell Line
10h 18m$118–242Drive 290.6 mi
- Drive from Syracuse to Lowellcar 290.6 mi
6h 15m$53–77Train to Rochester, fly
- Take the train from Syracuse Regional Transportation Center to Rochestertrain
- Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane ROC - BOS
5h 47m$117–602Bus to Buffalo Niagara International Airport, fly
- Take the bus from Syracuse Bus Station to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane BUF - BOS
7h 3m$108–526Bus, train
- Take the bus from Syracuse Bus Station to Albanybus
- Take the bus from Albany to Bostonbus
- Take the train from North Station to Lowelltrain
9h 6m$58–101
Syracuse to Lowell by bus
Questions & Answers
The cheapest way to get from Syracuse to Lowell is to bus which costs $50 - $100 and takes 8h 10m.
The fastest way to get from Syracuse to Lowell is to fly and train which takes 4h 37m and costs $70 - $430.
No, there is no direct bus from Syracuse station to Lowell. However, there are services departing from Syracuse Bus Station and arriving at Robert B Kennedy Bus Transfer Center via Boston. The journey, including transfers, takes approximately 8h 10m.
No, there is no direct train from Syracuse to Lowell. However, there are services departing from Syracuse Regional Transportation Center and arriving at Lowell via Back Bay and North Station. The journey, including transfers, takes approximately 10h 18m.
The distance between Syracuse and Lowell is 307 miles. The road distance is 292.3 miles.
The best way to get from Syracuse to Lowell without a car is to bus which takes 8h 10m and costs $50 - $100.
It takes approximately 4h 37m to get from Syracuse to Lowell, including transfers.
Syracuse to Lowell bus services, operated by Greyhound USA, depart from Syracuse Bus Station.
Syracuse to Lowell train services, operated by Amtrak, depart from Syracuse Regional Transportation Center station.
The best way to get from Syracuse to Lowell is to bus which takes 8h 10m and costs $50 - $100. Alternatively, you can train, which costs $110 - $250 and takes 10h 18m.
What companies run services between Syracuse, NY, USA and Lowell, MA, USA?
You can take a bus from Syracuse Bus Station to Robert B Kennedy Bus Transfer Center via Boston in around 8h 10m. Alternatively, you can take a train from Syracuse Regional Transportation Center to Lowell via Boston, Back Bay, North Station, and North Station in around 10h 18m.
- Website
- aa.com
Flights from Syracuse Hancock International Airport to Boston Logan Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $60–400
Flights from Rochester to Boston Logan Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $65–400
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $70–420
Flights from Buffalo Niagara International Airport to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 3h 41m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–440
- Website
- jetblue.com
Flights from Syracuse Hancock International Airport to Boston Logan Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $60–400
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $70–420
- Website
- southwest.com
Flights from Rochester to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 47m
- When
- Sunday and Saturday
- Estimated price
- $90–480
Flights from Buffalo Niagara International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 40m
- When
- Monday, Thursday, and Friday
- Estimated price
- $90–490
- Website
- united.com
Flights from Rochester to Boston Logan Airport via Newark
- Ave. Duration
- 3h 48m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–430
Flights from Buffalo Niagara International Airport to Boston Logan Airport via Newark
- Ave. Duration
- 3h 41m
- When
- Saturday
- Estimated price
- $75–440
Train from Anderson/Woburn to Lowell
- Ave. Duration
- 24 min
- Frequency
- Hourly
- Estimated price
- $2–8
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $2–8
Train from North Station to Lowell
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from North Station to Lowell
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Boston
- Ave. Duration
- 8h 42m
- Frequency
- Once daily
- Estimated price
- $110–230
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Rochester
- Ave. Duration
- 1h 16m
- Frequency
- 5 times a day
- Estimated price
- $25–55
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Syracuse Regional Transportation Center to Rochester
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- $21–170
- Website
- VIA Rail
- Escape
- $21–75
- Business
- $50–160
- Business Plus
- $65–170
- Economy
- $24–80
- Economy Plus
- $26–90
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 6h 25m
- Frequency
- 4 times a day
- Estimated price
- $45–90
- Website
- Greyhound
Bus from Boston to Robert B Kennedy Bus Transfer Center
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $4–8
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 6h 30m
- Frequency
- 6 times a week
- Estimated price
- $45–85
- Schedules at
- Flixbus USA
Bus from Syracuse Bus Station to Buffalo Niagara International Airport
- Ave. Duration
- 2h 45m
- Frequency
- Every 2 hours
- Estimated price
- $24–40
- Schedules at
- Flixbus USA
Bus from Syracuse Bus Station to Albany
- Ave. Duration
- 2h 45m
- Frequency
- 6 times a week
- Estimated price
- $22–40
- Schedules at
- Flixbus USA
Bus from Albany to Boston
- Ave. Duration
- 3h 40m
- Frequency
- 6 times a week
- Estimated price
- $28–50
- Schedules at
- Flixbus USA
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Syracuse Bus Station to Buffalo Niagara International Airport
- Saver
- $27–85
- Flexible
- $50–90
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More Questions & Answers
Syracuse to Lowell bus services, operated by Greyhound USA, arrive at Boston station.
Syracuse to Lowell train services, operated by Amtrak, arrive at Boston station.
Yes, the driving distance between Syracuse to Lowell is 292 miles. It takes approximately 6h 15m to drive from Syracuse to Lowell.
Book your Syracuse to Lowell bus tickets online with Omio and FlixBus.
There are 105+ hotels available in Lowell.


















