There are 8 ways to get from Syracuse to Middleborough by bus, train, train (Amtrak), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Syracuse Bus Station to Bostonbus Greyhound US0171 / ...
- Take the train from South Station to Middleboroughtrain Fall River/New Bedford Line
8h 16m$53–101Train
- Take the train from Syracuse Regional Transportation Center to Bostontrain Lake Shore Limited
- Take the train from South Station to Middleboroughtrain Fall River/New Bedford Line
10h 41m$117–242Drive 327.3 mi
- Drive from Syracuse to Middleboroughcar 327.3 mi
5h 43m$60–87Fly Syracuse Hancock International Airport to Boston Logan Airport, train
- Fly from Syracuse Hancock International Airport (SYR) to Boston Logan Airport (BOS)plane SYR - BOS
- Take the train from South Station to Middleboroughtrain
4h 58m$68–424Bus, train via West Albany
- Take the bus from Syracuse Bus Station to Albanybus
- Take the bus from Albany to Bostonbus
- Take the train from South Station to Middleboroughtrain
9h 16m$57–100Fly Syracuse Hancock International Airport to Provincetown Municipal Airport, drive
- Fly from Syracuse Hancock International Airport (SYR) to Provincetown Municipal Airport (PVC)plane SYR - PVC
- Drive from Provincetown Municipal Airport (PVC) to Middleboroughcar
6h 46m$92–512Train to Rochester, fly to Boston Logan Airport, train
- Take the train from Syracuse Regional Transportation Center to Rochestertrain
- Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane ROC - BOS
- Take the train from South Station to Middleboroughtrain
6h 8m$113–600Fly Syracuse Hancock International Airport to Barnstable Municipal Airport, train
- Fly from Syracuse Hancock International Airport (SYR) to Barnstable Municipal Airport (HYA)plane SYR - HYA
- Take the train from Hyannis to Lakevilletrain
9h 32m$87–581
Syracuse to Middleborough by bus and train
Questions & Answers
The cheapest way to get from Syracuse to Middleborough is to bus and train which costs $50 - $110 and takes 8h 16m.
The fastest way to get from Syracuse to Middleborough is to fly and train which takes 4h 58m and costs $65 - $430.
No, there is no direct train from Syracuse to Middleborough. However, there are services departing from Syracuse Regional Transportation Center and arriving at Middleborough via South Station. The journey, including transfers, takes approximately 10h 41m.
The distance between Syracuse and Middleborough is 348 miles. The road distance is 329.2 miles.
The best way to get from Syracuse to Middleborough without a car is to bus and train which takes 8h 16m and costs $50 - $110.
It takes approximately 8h 16m to get from Syracuse to Middleborough, including transfers.
Syracuse to Middleborough train services, operated by Amtrak, depart from Syracuse Regional Transportation Center station.
Syracuse to Middleborough train services, operated by Amtrak, arrive at Boston station.
Yes, the driving distance between Syracuse to Middleborough is 329 miles. It takes approximately 5h 43m to drive from Syracuse to Middleborough.
There are 82+ hotels available in Middleborough.
What companies run services between Syracuse, NY, USA and Middleborough, MA, USA?
You can take a train from Syracuse Regional Transportation Center to Middleborough via Boston and South Station in around 10h 41m.
- Website
- jetblue.com
Flights from Syracuse Hancock International Airport to Boston Logan Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $60–400
Flights from Syracuse Hancock International Airport to Provincetown Municipal Airport via Boston Logan Airport
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- $75–480
Flights from Syracuse Hancock International Airport to Provincetown Municipal Airport via New York JFK, Boston Logan Airport
- Ave. Duration
- 7h 12m
- When
- Every day
- Estimated price
- $85–550
Flights from Syracuse Hancock International Airport to Provincetown Municipal Airport via New York La Guardia, Boston Logan Airport
- Ave. Duration
- 5h 48m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–550
Flights from Syracuse Hancock International Airport to Provincetown Municipal Airport via Washington Dulles, Boston Logan Airport
- Ave. Duration
- 6h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Syracuse Hancock International Airport to Barnstable Municipal Airport via Boston Logan Airport
- Ave. Duration
- 4h 31m
- When
- Monday, Thursday, and Sunday
- Estimated price
- $80–550
- Website
- aa.com
Flights from Syracuse Hancock International Airport to Boston Logan Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $60–400
Flights from Rochester to Boston Logan Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $65–400
Flights from Syracuse Hancock International Airport to Barnstable Municipal Airport via Reagan Washington
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $120–650
Flights from Syracuse Hancock International Airport to Barnstable Municipal Airport via New York La Guardia
- Ave. Duration
- 6h 52m
- When
- Every day
- Estimated price
- $90–550
- Website
- capeair.com
Flights from Syracuse Hancock International Airport to Provincetown Municipal Airport via Boston Logan Airport
- Ave. Duration
- 3h 8m
- When
- Every day
- Estimated price
- $75–480
Flights from Syracuse Hancock International Airport to Provincetown Municipal Airport via New York La Guardia, Boston Logan Airport
- Ave. Duration
- 5h 48m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–550
Flights from Syracuse Hancock International Airport to Provincetown Municipal Airport via Philadelphia, Boston Logan Airport
- Ave. Duration
- 5h 51m
- When
- Sunday
- Estimated price
- $100–550
Flights from Syracuse Hancock International Airport to Provincetown Municipal Airport via Washington Dulles, Boston Logan Airport
- Ave. Duration
- 6h 3m
- When
- Sunday, Monday, Tuesday, Wednesday, Thursday, and Friday
- Estimated price
- $120–650
Flights from Syracuse Hancock International Airport to Barnstable Municipal Airport via Boston Logan Airport
- Ave. Duration
- 4h 21m
- When
- Monday, Thursday, and Sunday
- Estimated price
- $80–550
- Website
- southwest.com
Flights from Rochester to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 47m
- When
- Sunday and Saturday
- Estimated price
- $90–480
- Website
- united.com
Flights from Rochester to Boston Logan Airport via Newark
- Ave. Duration
- 3h 48m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–430
Train from South Station to Middleborough
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- $6–13
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $6–13
Train from South Station to Middleborough
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- $6–13
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $6–13
Train from South Station to Middleborough
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- $6–13
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $6–13
Train from South Station to Middleborough
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- $6–13
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $6–13
Train from South Station to Middleborough
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- $6–13
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $6–13
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Boston
- Ave. Duration
- 8h 50m
- Frequency
- Once daily
- Estimated price
- $110–230
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Rochester
- Ave. Duration
- 1h 16m
- Frequency
- 5 times a day
- Estimated price
- $25–55
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Syracuse Regional Transportation Center to Rochester
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- $21–170
- Website
- VIA Rail
- Escape
- $21–75
- Business
- $50–150
- Business Plus
- $65–170
- Economy
- $24–80
- Economy Plus
- $26–90
- Phone
- +1 508-775-8504
- [email protected]
- Website
- CapeFlyer
Train from Hyannis to Lakeville
- Ave. Duration
- 1h 33m
- Frequency
- 3 times a week
- Estimated price
- $5–22
- Website
- CapeFlyer
- South Station to Bourne
- $20
- South Station to Hyannis
- $22
- Middleborough to Hyannis
- $5
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 6h 25m
- Frequency
- 4 times a day
- Estimated price
- $45–90
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 6h 30m
- Frequency
- 6 times a week
- Estimated price
- $45–85
- Schedules at
- Flixbus USA
Bus from Syracuse Bus Station to Albany
- Ave. Duration
- 2h 45m
- Frequency
- 6 times a week
- Estimated price
- $22–40
- Schedules at
- Flixbus USA
Bus from Albany to Boston
- Ave. Duration
- 3h 40m
- Frequency
- 6 times a week
- Estimated price
- $28–50
- Schedules at
- Flixbus USA
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