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How to get fromSyracuse to Middletown (Station)by bus (Greyhound), train (Amtrak), car, plane, bus, or train

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There are 6 ways to get from Syracuse to Middletown (Station) by bus (Greyhound), train (Amtrak), car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Syracuse Bus Station to Scranton Bus Stationbus bus Greyhound US0215
    2. Take the bus from Scranton, Pa to Harrisburg, Pabus bus 771
    7h 56m
    $45–115

  2. Train (Amtrak)

    1. Take the train from Syracuse Regional Transportation Center to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Middletowntrain train Keystone Service
    9h 50m
    $143–305

  3. Drive 250.7 mi

    1. Drive from Syracuse to Middletown (Station)car car 250.7 mi
    4h 37m
    $46–67

  4. Fly to Harrisburg International Airport

    1. Fly from Syracuse Hancock International Airport (SYR) to Harrisburg International Airport (MDT)plane plane SYR - MDT
    5h 30m
    $66–458

  5. Bus, train

    1. Take the bus from Syracuse to Newarkbus bus Adt N813 / ...
    2. Take the train from Newark Penn Station to Middletowntrain train Keystone Service
    7h 59m
    $87–262

  6. Fly to Philadelphia International Airport, train

    1. Fly from Syracuse Hancock International Airport (SYR) to Philadelphia International Airport (PHL)plane plane SYR - PHL
    2. Take the train from 30th Street Station to Middletowntrain train
    6h 13m
    $112–621

Syracuse to Middletown (Station) by bus and foot

Calendar7Weekly Services
Duration7h 56mAverage Duration
Ticket$45Cheapest Price
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Questions & Answers

Map of how to get from Syracuse to Middletown (Station).ExpandLaunch map view
  • Distance: 270.1 mi
  • Duration: 7h 56m

What companies run services between Syracuse, NY, USA and Middletown (Station), PA, USA?

You can take a bus from Syracuse Bus Station to Ann St & S Lawrence St WB via Scranton, Pa, Harrisburg, Pa, and Market Square Transfer Center in around 7h 56m. Alternatively, you can take a train from Syracuse Regional Transportation Center to Middletown via Ny Moynihan Train Hall At Penn Station in around 9h 50m.

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