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How to get fromSyracuse to Myrtle Beachby plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound)

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There are 7 ways to get from Syracuse to Myrtle Beach by plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Syracuse Hancock International Airport

    best
    1. Fly from Syracuse Hancock International Airport (SYR) to Myrtle Beach (MYR)plane plane SYR - MYR
    3h 43m
    $452–822

  2. Bus via Wilmington

    cheapest
    1. Take the bus from Syracuse Bus Station to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Wilmington Cape Fear Public Transitbus bus
    4. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    21h 25m
    $140–276

  3. Bus, train

    1. Take the bus from Syracuse Bus Station to Newark Penn Stationbus bus
    2. Take the train from Newark Penn Station to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    22h 40m
    $271–568

  4. Drive 776.9 mi

    1. Drive from Syracuse to Myrtle Beachcar car 776.9 mi
    14h 28m
    $142–205

  5. Train to Rochester, fly

    1. Take the train from Syracuse Regional Transportation Center to Rochestertrain train
    2. Fly from Rochester (ROC) to Myrtle Beach (MYR)plane plane ROC - MYR
    4h 29m
    $232–898

  6. Train, bus

    1. Take the train from Syracuse Regional Transportation Center to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Fayetteville Amtrak Stationtrain train
    3. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    27h 16m
    $318–661

  7. Bus

    1. Take the bus from Syracuse to New Yorkbus bus
    2. Take the bus from New York, NY to Fayetteville, NCbus bus Nyc
    3. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    27h 27m
    $178–378

Syracuse to Myrtle Beach by bus

Calendar14Weekly Buses
Duration21h 25mAverage Duration
Ticket$140Cheapest Price
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Questions & Answers

Map of how to get from Syracuse to Myrtle Beach.ExpandLaunch map view
  • Distance: 686.1 mi
  • Duration: 3h 43m

What companies run services between Syracuse, NY, USA and Myrtle Beach, SC, USA?

Allegiant Air, Delta, and American Airlines fly from Syracuse Hancock International Airport (SYR) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a bus from Syracuse Bus Station to Myrtle Beach Bus Station via Newark Penn Station, Raleigh Bus Station, and Wilmington Cape Fear Public Transit in around 21h 25m.

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