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How to get fromSyracuse to Ohioby plane, bus (Greyhound), train, bus, car, or bus (Flixbus)

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There are 7 ways to get from Syracuse to Ohio by plane, bus (Greyhound), train, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Cleveland-Hopkins International Airport

    best
    1. Fly from Syracuse Hancock International Airport (SYR) to Cleveland-Hopkins International Airport (CLE)plane plane SYR - CLE
    5h 53m
    $114–661

  2. Bus via Buffalo

    cheapest
    1. Take the bus from Syracuse Bus Station to Buffalo Niagara International Airportbus bus FlixBus 2686 / ...
    2. Take the bus from Buffalo, NY to Columbus - Mound Stbus bus Buffalo
    11h 43m
    $64–198

  3. Bus (Greyhound)

    1. Take the bus from Syracuse Bus Station to Cleveland Bus Stationbus bus Greyhound US0171
    2. Take the bus from Cleveland Bus Station to Columbusbus bus Greyhound US0105
    10h 15m
    $74–142

  4. Train, bus via Brook Park

    1. Take the train from Syracuse Regional Transportation Center to Cleveland Amtraktrain train Lake Shore Limited
    2. Take the bus from Cleveland Bus Station to Columbusbus bus Greyhound US0105
    10h 20m
    $127–258

  5. Drive 469.8 mi

    1. Drive from Syracuse to Columbuscar car 469.8 mi
    8h 2m
    $86–124

  6. Fly to Detroit, bus

    1. Fly from Syracuse Hancock International Airport (SYR) to Detroit (DTW)plane plane SYR - DTW
    2. Take the bus from Dearborn to Toledobus bus
    6h 31m
    $128–654

  7. Train, bus

    1. Take the train from Syracuse Regional Transportation Center to Cleveland Amtraktrain train Lake Shore Limited
    2. Take the bus from Cleveland Ohio Greyhound Station to Columbus, Ohio Greyhound Stationbus bus 379 D
    12h 30m
    $165–299

Syracuse to Ohio by bus (Greyhound)

Calendar14Weekly Buses
Duration10h 15mAverage Duration
Ticket$74Cheapest Price
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Questions & Answers

Map of how to get from Syracuse to Ohio.ExpandLaunch map view
  • Distance: 340.9 mi
  • Duration: 5h 53m

What companies run services between Syracuse, NY, USA and Ohio, USA?

United Airlines, Delta, and American Airlines fly from Syracuse Hancock International Airport (SYR) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, you can take a bus from Syracuse Bus Station to Columbus via Cleveland Bus Station in around 10h 15m.

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