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How to get fromSyracuse to Pittsburghby bus (Flixbus, Greyhound), train (Amtrak), car, plane, or bus

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There are 6 ways to get from Syracuse to Pittsburgh by bus (Flixbus, Greyhound), train (Amtrak), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Youngstown

    best
    1. Take the bus from Syracuse Bus Station to Buffalobus bus
    2. Take the bus from Buffalo, NY to Youngstown, OHbus bus
    3. Take the bus from Youngstown Bus Stop to Pittsburgh Intermodal Stationbus bus
    9h 15m
    $56–169

  2. Train (Amtrak)

    1. Take the train from Syracuse Regional Transportation Center to Cleveland Amtraktrain train Lake Shore Limited
    2. Take the train from Cleveland Amtrak to Pittsburgh Amtrak Stationtrain train Floridian
    9h 59m
    $144–310

  3. Drive 359.7 mi

    1. Drive from Syracuse to Pittsburghcar car 359.7 mi
    6h 13m
    $66–95

  4. Fly from Syracuse Hancock International Airport

    1. Fly from Syracuse Hancock International Airport (SYR) to Pittsburgh International Airport (PIT)plane plane SYR - PIT
    6h 39m
    $361–808

  5. Bus

    1. Take the bus from Syracuse Bus Station to Buffalobus bus FlixBus 2686 / ...
    2. Take the bus from Buffalo to Pittsburghbus bus Fab530
    11h 35m
    $129–295

  6. Bus to Ithaca Tompkins Regional Airport, fly

    1. Take the bus from Syracuse Bus Station to Ithacabus bus
    2. Fly from Ithaca Tompkins Regional Airport (ITH) to Pittsburgh International Airport (PIT)plane plane ITH - PIT
    8h 20m
    $75–396

Syracuse to Pittsburgh by bus

Calendar7Weekly Buses
Duration9h 15mAverage Duration
Ticket$56Cheapest Price
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Questions & Answers

Map of how to get from Syracuse to Pittsburgh.ExpandLaunch map view
  • Distance: 404.5 mi
  • Duration: 9h 15m

What companies run services between Syracuse, NY, USA and Pittsburgh, PA, USA?

You can take a bus from Syracuse Bus Station to Pittsburgh Intermodal Station via Buffalo, Buffalo, NY, Youngstown, OH, and Youngstown Bus Stop in around 9h 15m. Alternatively, you can take a train from Syracuse Regional Transportation Center to Pittsburgh Amtrak Station via Cleveland Amtrak in around 9h 59m.

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