There are 6 ways to get from Syracuse to Waltham by plane, bus, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Syracuse Hancock International Airport, line 504 bus
best- Fly from Syracuse Hancock International Airport (SYR) to Boston Logan Airport (BOS)plane SYR - BOS
- Take the bus from Saint James Ave @ Dartmouth St to Washington St @ Bacon Stbus
3h 43m$71–422Bus
cheapest- Take the bus from Syracuse Bus Station to Bostonbus Greyhound US0171 / ...
8h 15m$48–93Train (Amtrak)
- Take the train from Syracuse Regional Transportation Center to Bostontrain Lake Shore Limited
9h 9m$110–233Drive 301.5 mi
- Drive from Syracuse to Walthamcar 301.5 mi
5h 17m$55–80Train to Rochester, fly
- Take the train from Syracuse Regional Transportation Center to Rochestertrain
- Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane ROC - BOS
4h 52m$116–598Bus via West Albany (Flixbus)
- Take the bus from Syracuse Bus Station to Albanybus FlixBus 2691
- Take the bus from Albany to Bostonbus FlixBus 2691
9h 19m$50–86
Syracuse to Waltham by bus and foot
Questions & Answers
The cheapest way to get from Syracuse to Waltham is to bus via West Albany which costs $50 - $90 and takes 9h 19m.
The fastest way to get from Syracuse to Waltham is to fly and line 504 bus which takes 3h 43m and costs $70 - $430.
No, there is no direct bus from Syracuse station to Waltham. However, there are services departing from Syracuse Bus Station and arriving at Moody St @ Carter St via Otis St @ Summer St. The journey, including transfers, takes approximately 8h 15m.
No, there is no direct train from Syracuse to Waltham. However, there are services departing from Syracuse Regional Transportation Center and arriving at Boston via . The journey, including transfers, takes approximately 9h 9m.
The distance between Syracuse and Waltham is 296 miles. The road distance is 303.2 miles.
The best way to get from Syracuse to Waltham without a car is to bus which takes 8h 15m and costs $45 - $95.
It takes approximately 3h 43m to get from Syracuse to Waltham, including transfers.
Syracuse to Waltham bus services, operated by Greyhound USA, depart from Syracuse Bus Station.
Syracuse to Waltham train services, operated by Amtrak, depart from Syracuse Regional Transportation Center station.
The best way to get from Syracuse to Waltham is to bus which takes 8h 15m and costs $45 - $95. Alternatively, you can train, which costs $110 - $240 and takes 9h 9m.
What companies run services between Syracuse, NY, USA and Waltham, MA, USA?
Greyhound USA operates a bus from Syracuse Bus Station to Boston 4 times a day. Tickets cost $45–90 and the journey takes 6h 25m. Flixbus USA also services this route 6 times a week. Alternatively, Amtrak operates a train from Syracuse Regional Transportation Center to Boston once daily. Tickets cost $100–230 and the journey takes 8h 42m.
- Website
- aa.com
Flights from Syracuse Hancock International Airport to Boston Logan Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $60–400
Flights from Rochester to Boston Logan Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $65–400
- Website
- southwest.com
Flights from Rochester to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 47m
- When
- Sunday and Saturday
- Estimated price
- $90–480
- Website
- jetblue.com
Flights from Syracuse Hancock International Airport to Boston Logan Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $60–400
- Website
- united.com
Flights from Rochester to Boston Logan Airport via Newark
- Ave. Duration
- 3h 48m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–430
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Boston
- Ave. Duration
- 8h 42m
- Frequency
- Once daily
- Estimated price
- $100–230
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Rochester
- Ave. Duration
- 1h 16m
- Frequency
- 5 times a day
- Estimated price
- $25–55
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Syracuse Regional Transportation Center to Rochester
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- $21–170
- Website
- VIA Rail
- Escape
- $21–75
- Business
- $50–160
- Business Plus
- $65–170
- Economy
- $24–80
- Economy Plus
- $26–90
Bus from Saint James Ave @ Dartmouth St to Washington St @ Bacon St
- Ave. Duration
- 9 min
- Frequency
- Every 30 minutes
- Estimated price
- $1–5
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 6h 25m
- Frequency
- 4 times a day
- Estimated price
- $45–90
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 6h 30m
- Frequency
- 6 times a week
- Estimated price
- $45–80
- Schedules at
- Flixbus USA
Bus from Syracuse Bus Station to Albany
- Ave. Duration
- 2h 45m
- Frequency
- 6 times a week
- Estimated price
- $22–40
- Schedules at
- Flixbus USA
Bus from Albany to Boston
- Ave. Duration
- 3h 40m
- Frequency
- 6 times a week
- Estimated price
- $27–45
- Schedules at
- Flixbus USA
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More Questions & Answers
Syracuse to Waltham bus services, operated by Greyhound USA, arrive at Boston station.
Syracuse to Waltham train services, operated by Amtrak, arrive at Boston station.
Yes, the driving distance between Syracuse to Waltham is 303 miles. It takes approximately 5h 17m to drive from Syracuse to Waltham.
There are 1584+ hotels available in Waltham.















