There are 3 ways to get from Syracuse, Ny to Buffalo by train (Amtrak), bus (Flixbus, Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Syracuse, Ny to Buffalo by train
Comparing Your Travel Options
The cheapest way to get from Syracuse, Ny to Buffalo is to drive which costs $25 - $40 and takes 2h 39m.
The fastest way to get from Syracuse, Ny to Buffalo is to drive which takes 2h 39m and costs $25 - $40.
Yes, there is a direct bus departing from Syracuse Bus Station station and arriving at Buffalo. Services depart hourly, and operate every day. The journey takes approximately 3h 5m.
Yes, there is a direct train departing from Syracuse Regional Transportation Center and arriving at Buffalo. Services depart four times a day, and operate every day. The journey takes approximately 2h 53m.
The distance between Syracuse, Ny and Buffalo is 149 miles. The road distance is 148.6 miles.
The best way to get from Syracuse, Ny to Buffalo without a car is to train which takes 2h 53m and costs $35 - $190.
The train from Syracuse Regional Transportation Center to Buffalo takes 2h 53m including transfers and departs four times a day.
Syracuse, Ny to Buffalo bus services, operated by Flixbus USA, depart from Syracuse Bus Station.
Syracuse, Ny to Buffalo train services, operated by Amtrak, depart from Syracuse Regional Transportation Center station.
The best way to get from Syracuse, Ny to Buffalo is to train which takes 2h 53m and costs $35 - $190. Alternatively, you can bus, which costs $28 - $95 and takes 3h 5m.
What companies run services between Syracuse, Ny, NY, USA and Buffalo, NY, USA?
Amtrak operates a train from Syracuse Regional Transportation Center to Buffalo 3 times a day. Tickets cost $80–130 and the journey takes 2h 53m. VIA Rail also services this route once daily. Alternatively, Flixbus USA operates a bus from Syracuse Bus Station to Buffalo every 2 hours. Tickets cost $25–40 and the journey takes 3h 5m. Two other operators also service this route.
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Buffalo
- Ave. Duration
- 2h 53m
- Frequency
- 3 times a day
- Estimated price
- $80–130
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Syracuse Regional Transportation Center to Buffalo
- Ave. Duration
- 2h 33m
- Frequency
- Once daily
- Estimated price
- $35–190
- Website
- VIA Rail
- Escape
- $35–110
- Business
- $70–170
- Business Plus
- $80–190
- Economy
- $40–120
- Economy Plus
- $45–120
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 5m
- Frequency
- Every 2 hours
- Estimated price
- $25–40
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h
- Frequency
- Every 3 hours
- Estimated price
- $29–45
- Website
- Greyhound
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Syracuse Bus Station to Buffalo
- Saver
- $28–90
- Flexible
- $55–95
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Syracuse, Ny to Buffalo bus services, operated by Flixbus USA, arrive at Buffalo station.
Syracuse, Ny to Buffalo train services, operated by Amtrak, arrive at Buffalo station.
Yes, the driving distance between Syracuse, Ny to Buffalo is 149 miles. It takes approximately 2h 39m to drive from Syracuse, Ny to Buffalo.
Book your Syracuse, Ny to Buffalo train tickets online with Omio.
Book your Syracuse, Ny to Buffalo bus tickets online with Omio and FlixBus.
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