There are 7 ways to get from Syracuse, Ny to Salem by plane, train, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Syracuse Hancock International Airport, train
best- Fly from Syracuse Hancock International Airport (SYR) to Boston Logan Airport (BOS)plane SYR - BOS
- Take the train from Chelsea to Salemtrain
4h 15m$64–441Bus
cheapest- Take the bus from Syracuse Bus Station to Bostonbus Greyhound US0171 / ...
8h 36m$48–93Train (Amtrak)
- Take the train from Syracuse Regional Transportation Center to Bostontrain Lake Shore Limited
9h 53m$114–239Drive 323 mi
- Drive from Syracuse, Ny to Salemcar 323 mi
5h 49m$59–86Train to Rochester, fly
- Take the train from Syracuse Regional Transportation Center to Rochestertrain
- Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane ROC - BOS
5h 18m$104–607Bus to Buffalo Niagara International Airport, fly
- Take the bus from Syracuse Bus Station to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane BUF - BOS
6h 34m$95–502Bus via West Albany (Flixbus)
- Take the bus from Syracuse Bus Station to Albanybus FlixBus 2691
- Take the bus from Albany to Bostonbus FlixBus 2691
8h 44m$52–93
Syracuse, Ny to Salem by bus and foot
Questions & Answers
The cheapest way to get from Syracuse, Ny to Salem is to bus which costs $45 - $95 and takes 8h 36m.
The fastest way to get from Syracuse, Ny to Salem is to fly and train which takes 4h 15m and costs $60 - $450.
No, there is no direct bus from Syracuse, Ny station to Salem. However, there are services departing from Syracuse Bus Station and arriving at Washington St @ New Derby St via Devonshire St @ Milk St and Congress St @ Haymarket Sta. The journey, including transfers, takes approximately 8h 36m.
No, there is no direct train from Syracuse, Ny to Salem. However, there are services departing from Syracuse Regional Transportation Center and arriving at Salem via Back Bay and North Station. The journey, including transfers, takes approximately 9h 53m.
The distance between Syracuse, Ny and Salem is 293 miles. The road distance is 324.9 miles.
The best way to get from Syracuse, Ny to Salem without a car is to bus which takes 8h 36m and costs $45 - $95.
It takes approximately 4h 15m to get from Syracuse, Ny to Salem, including transfers.
Syracuse, Ny to Salem bus services, operated by Greyhound USA, depart from Syracuse Bus Station.
Syracuse, Ny to Salem train services, operated by Amtrak, depart from Syracuse Regional Transportation Center station.
The best way to get from Syracuse, Ny to Salem is to bus which takes 8h 36m and costs $45 - $95. Alternatively, you can train, which costs $110 - $240 and takes 9h 53m.
What companies run services between Syracuse, Ny, NY, USA and Salem, MA, USA?
Greyhound USA operates a bus from Syracuse Bus Station to Boston twice daily. Tickets cost $45–90 and the journey takes 6h 25m. Flixbus USA also services this route 3 times a week. Alternatively, Amtrak operates a train from Syracuse Regional Transportation Center to Boston once daily. Tickets cost $100–230 and the journey takes 8h 42m.
- Website
- aa.com
Flights from Syracuse Hancock International Airport to Boston Logan Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $60–420
Flights from Rochester to Boston Logan Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $60–410
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $65–400
Flights from Buffalo Niagara International Airport to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 3h 41m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–420
- Website
- jetblue.com
Flights from Syracuse Hancock International Airport to Boston Logan Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $60–420
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $65–400
- Website
- southwest.com
Flights from Rochester to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 47m
- When
- Sunday and Saturday
- Estimated price
- $90–490
Flights from Buffalo Niagara International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 40m
- When
- Monday, Thursday, and Friday
- Estimated price
- $85–470
- Website
- united.com
Flights from Rochester to Boston Logan Airport via Newark
- Ave. Duration
- 3h 48m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–440
Flights from Buffalo Niagara International Airport to Boston Logan Airport via Newark
- Ave. Duration
- 3h 41m
- When
- Saturday
- Estimated price
- $70–420
Train from Chelsea to Salem
- Ave. Duration
- 21 min
- Frequency
- Hourly
- Estimated price
- $2–8
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $2–8
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Boston
- Ave. Duration
- 8h 42m
- Frequency
- Once daily
- Estimated price
- $100–230
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Rochester
- Ave. Duration
- 1h 16m
- Frequency
- 5 times a day
- Estimated price
- $24–55
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Syracuse Regional Transportation Center to Rochester
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- $21–170
- Website
- VIA Rail
- Escape
- $21–75
- Business
- $50–150
- Business Plus
- $65–170
- Economy
- $24–80
- Economy Plus
- $26–90
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 6h 25m
- Frequency
- Twice daily
- Estimated price
- $45–90
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a week
- Estimated price
- $45–80
- Schedules at
- Flixbus USA
Bus from Syracuse Bus Station to Buffalo Niagara International Airport
- Ave. Duration
- 2h 45m
- Frequency
- Every 4 hours
- Estimated price
- $23–40
- Schedules at
- Flixbus USA
Bus from Syracuse Bus Station to Albany
- Ave. Duration
- 2h 45m
- Frequency
- 3 times a week
- Estimated price
- $21–40
- Schedules at
- Flixbus USA
Bus from Albany to Boston
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a week
- Estimated price
- $27–45
- Schedules at
- Flixbus USA
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Syracuse Bus Station to Buffalo Niagara International Airport
- Saver
- $27–85
- Flexible
- $50–90
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More Questions & Answers
Syracuse, Ny to Salem bus services, operated by Greyhound USA, arrive at Boston station.
Syracuse, Ny to Salem train services, operated by Amtrak, arrive at Boston station.
Yes, the driving distance between Syracuse, Ny to Salem is 325 miles. It takes approximately 5h 49m to drive from Syracuse, Ny to Salem.
There are 1284+ hotels available in Salem.

















