There are 8 ways to get from Sète to Lyon by train (TGV), bus, rideshare, plane, train (TGV, Renfe), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (TGV)
best- Take the train from Sete to Lyon Part Dieutrain Tgv
2h 9m€60–95Rideshare
cheapest- Take the rideshare from Sète to Lyon331.7 km
3h 43m€18–30Line 602 bus, bus
- Take the bus from Sete - Noel Guignon to Montpellier - Sabines Tw2bus 602
- Take the bus from Montpellier - Sabines Bus Station to Lyon - Gerland Bus Stationbus BlaBlaCar Bus
4h 57m€22–42Bus to Fréjorgues Airport, fly
- Take the bus from Sète to Montpellier - Aeroport Montpellierbus
- Fly from Fréjorgues Airport (MPL) to Lyon–Saint Exupéry Airport (LYS)plane MPL - LYS
5h 51m€204–434Train via Saint-Marcel-lès-Valence
- Take the train from Sete to Valence Tgv Rhone-Alpes Sudtrain Tgv
- Take the train from Valence Tgv Rhone-Alpes Sud to Lyon Part Dieutrain Tgv
2h 32m€57–97Line 602 bus, bus via Lyon, Perrache Bus Station
- Take the bus from Sete - Noel Guignon to Montpellier - Sabines Tw2bus 602
- Take the bus from Montpellier to Lyon, Perrache Bus Stationbus
5h 10m€27–42Drive 329.5 km
- Drive from Sète to Lyoncar 329.5 km
3h 13m€52–76Train to Marseille Provence Airport, fly
- Take the train from Sete to Vitrolles Aeroport Marseilletrain
- Fly from Marseille Provence Airport (MRS) to Lyon–Saint Exupéry Airport (LYS)plane MRS - LYS
5h 2m€125–332
Sète to Lyon by train (TGV)
Comparing Your Travel Options
The cheapest way to get from Sète to Lyon is to rideshare which costs €18 - €30 and takes 3h 43m.
The fastest way to get from Sète to Lyon is to train which takes 2h 9m and costs €60 - €95.
No, there is no direct bus from Sète to Lyon station. However, there are services departing from Sete - Noel Guignon and arriving at Lyon - Gerland Bus Station via Montpellier - Sabines Bus Station. The journey, including transfers, takes approximately 4h 57m.
Yes, there is a direct train departing from Sete and arriving at Lyon Part Dieu. Services depart every four hours, and operate every day. The journey takes approximately 2h 9m.
The distance between Sète and Lyon is 335 km. The road distance is 329.5 km.
The best way to get from Sète to Lyon without a car is to train which takes 2h 9m and costs €60 - €95.
The train from Sete to Lyon Part Dieu takes 2h 9m including transfers and departs every four hours.
Sète to Lyon bus services, operated by Hérault - liO Occitanie, depart from Sete - Noel Guignon station.
Sète to Lyon train services, operated by TGV inOui, depart from Sete station.
The best way to get from Sète to Lyon is to train which takes 2h 9m and costs €60 - €95. Alternatively, you can line 602 bus and bus, which costs €22 - €45 and takes 4h 57m.
What companies run services between Sète, France and Lyon, France?
TGV inOui operates a train from Sete to Lyon Part Dieu every 4 hours. Tickets cost €60–95 and the journey takes 2h 9m. Alternatively, you can take a bus from Sete - Noel Guignon to Lyon - Gerland Bus Station via Montpellier - Sabines Tw2 and Montpellier - Sabines Bus Station in around 4h 57m.
- Website
- airfrance.com
Flights from Fréjorgues Airport to Lyon–Saint Exupéry Airport via Paris Charles de Gaulle
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- €90–490
Flights from Marseille Provence Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 55 min
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €35–270
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Sete to Lyon Part Dieu
- Ave. Duration
- 2h 9m
- Frequency
- Every 4 hours
- Estimated price
- €60–95
- Website
- TGV inOui
Train from Sete to Valence Tgv Rhone-Alpes Sud
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- €45–70
- Website
- TGV inOui
Train from Valence Tgv Rhone-Alpes Sud to Lyon Part Dieu
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €19–29
- Website
- TGV inOui
- Phone
- 04 34 88 89 99
- Website
- lio.laregion.fr
Bus from Sete - Noel Guignon to Montpellier - Sabines Tw2
- Ave. Duration
- 1h
- Frequency
- 5 times a day
- Estimated price
- €2
- Schedules at
- lio-occitanie.fr
Bus from Sete - Noel Guignon to Montpellier - Sabines Tw2
- Ave. Duration
- 1h
- Frequency
- 5 times a day
- Estimated price
- €2
- Schedules at
- lio-occitanie.fr
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar
Rideshare from Sète to Lyon
- Ave. Duration
- 3h 43m
- Frequency
- 3 times a day
- Estimated price
- €18–30
- Schedules at
- BlaBlaCar
Want to know more about travelling around France
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Sète to Lyon bus services, operated by Hérault - liO Occitanie, arrive at Montpellier - Sabines Tw2 station.
Sète to Lyon train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
Yes, the driving distance between Sète to Lyon is 329 km. It takes approximately 3h 13m to drive from Sète to Lyon.
Book your Sète to Lyon train tickets online with Omio.
Book your Sète to Lyon bus tickets online with Omio.
There are 3940+ hotels available in Lyon.
Check out Blablacar's carpooling service for rideshare options between Sète and Lyon. A great option if you don't have a driver's licence or want to avoid public transport.




