Rome2Rio

How to get fromTallahassee to Florenceby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

Find Transport to Florence

See all options

There are 6 ways to get from Tallahassee to Florence by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Regional Airport

    best
    1. Fly from Tallahassee (TLH) to Florence Regional Airport (FLO)plane plane TLH - FLO
    4h 24m
    $99–431

  2. Drive 407.1 mi

    cheapest
    1. Drive from Tallahassee to Florencecar car 407.1 mi
    7h 52m
    $75–108

  3. Bus

    1. Take the bus from Tallahassee to Jacksonvillebus bus Greyhound US0760S
    2. Take the bus from Jacksonville to Florencebus bus FlixBus N2472
    10h 6m
    $90–150

  4. Bus, train

    1. Take the bus from Tallahassee to Jacksonvillebus bus Greyhound US0760S
    2. Take the train from Jacksonville to Florence Stationtrain train Silver Meteor
    11h 27m
    $126–280

  5. Fly to Fayetteville Municipal Airport, train

    1. Fly from Tallahassee (TLH) to Fayetteville Municipal Airport (FAY)plane plane TLH - FAY
    2. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train
    6h 37m
    $136–492

  6. Bus via Sumter (Greyhound)

    1. Take the bus from Tallahassee to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Sumter Bus Stopbus bus
    3. Take the bus from Sumter Bus Stop to Florence Bus Stationbus bus
    12h 30m
    $75–149

Tallahassee to Florence by bus and train

Calendar7Weekly Services
Duration11h 27mAverage Duration
Ticket$126Cheapest Price
See schedules

Questions & Answers

Map of how to get from Tallahassee to Florence.ExpandLaunch map view
  • Distance: 384.8 mi
  • Duration: 4h 24m

What companies run services between Tallahassee, FL, USA and Florence, SC, USA?

American Airlines flies from Tallahassee (TLH) to Florence Regional Airport (FLO) 4 times a day. Alternatively, you can take a bus from Tallahassee to Florence via Jacksonville and Florence in around 10h 6m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers