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How to get fromTampa Airport (TPA) to Des Moinesby plane, bus (Flixbus, Greyhound), train, bus, or car

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There are 4 ways to get from Tampa Airport (TPA) to Des Moines by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Tampa (TPA) to Des Moines (DSM)plane plane TPA - DSM
    4h 54m
    $198–859

  2. Bus

    1. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Des Moinesbus bus
    32h 16m
    $212–402

  3. Train, bus

    1. Take the train from Tampa to Chicago Union Stationtrain train Floridian
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    2d 2h
    $606–1,301

  4. Drive 1,343 mi

    1. Drive from Tampa Airport (TPA) to Des Moinescar car 1,343 mi
    23h 21m
    $246–354

Tampa Airport (TPA) to Des Moines by bus

Calendar7Weekly Buses
Duration32h 16mAverage Duration
Ticket$212Cheapest Price
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Questions & Answers

Map of how to get from Tampa Airport (TPA) to Des Moines.ExpandLaunch map view
  • Distance: 1,133.7 mi
  • Duration: 4h 54m

What companies run services between Tampa Airport (TPA), USA and Des Moines, IA, USA?

Delta, Southwest Airlines, and two other airlines fly from Tampa (TPA) to Des Moines (DSM) hourly. Alternatively, you can take a bus from TPA Internat'l Airport Post Office to Des Moines via Marion Transit Center, Tampa Bus Station, Atlanta Bus Station, and St Louis Bus Station in around 32h 16m.

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